Evidence map›Paper›PMID 30094786›Full record

ReviewAnalytical and bioanalytical chemistry2018

Mass spectrometry-based shotgun lipidomics - a critical review from the technical point of view.

Fong-Fu Hsu

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Spatial MS multiomics on clinical prostate cancer tissues.Analytical and bioanalytical chemistry · 2024
    Article
  16. Article
  17. Review
  18. Insights into the CD1 lipidome.Frontiers in immunology · 2024
    Article
  19. Proteomics for Microalgae Extracts by High-Resolution Mass Spectrometry.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Fong-Fu HsuMass Spectrometry Resource, Division of Endocrinology, Diabetes, Metabolism, and Lipid Research, Department of Internal Medicine, Washington University School of Medicine, 660 S Euclid, St. Louis, MO, 63110, USA. fhsu@im.wustl.edu.

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
TRANSGENICS COREP60DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI SCHAFFER, JEAN E. · 1986 to 2012
$25.2M
TrainingP41GM103422 · NIGMS · WASHINGTON UNIVERSITY · PI YARASHESKI, KEVIN E · 2012 to 2019
$12.0M
Mechanisms of Innate Immune Evasion by Mycobacterium TuberculosisR01AI130454 · NIAID · WASHINGTON UNIVERSITY · PI JENNIFER A PHILIPS · 2017 to 2026
$5.9M
Lipidomic Screening For Functional Surfactant Gene MutationsR33HL120760 · NHLBI · WASHINGTON UNIVERSITY · PI COLE, FRANCIS SESSIONS · 2016 to 2018
$1.4M
NHLBI NIH HHS R33 HL120760NIAID NIH HHS R01 AI130454NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341NIGMS NIH HHS P41 GM103422NIH HHS R01AI130454
6 · The paper itself

Abstract

Over the past decade, mass spectrometry (MS)-based "shotgun lipidomics" has emerged as a powerful tool for quantitative and qualitative analysis of the complex lipids in the biological system. The aim of this critical review is to give the interested reader a concise overview of the current state of the technology, focused on lipidomic analysis by mass spectrometry. The pros and cons, and pitfalls associated with each available "shotgun lipidomics" method are discussed; and the new strategies for improving the current methods are described. A list of important papers and reviews that are sufficient rather than comprehensive, covering all the aspects of lipidomics including the workflow, methodology, and fundamentals is also compiled for readers to follow. Graphical abstract ᅟ.

Indexed as

HumansLipidsSpectrometry, Mass, Electrospray IonizationLipidsCollision induced dissociationElectrospray ionizationLipidLipidomicsMALDIMass spectrometry

Identifiers

PMID30094786
PMCPMC6195124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.