Evidence map›Paper›PMID 30094776›Full record

ArticleHead and neck pathology2019

Embryonal Rhabdomyosarcoma (Botryoid Subtype) Affecting the Buccal Mucosa.

John Lennon Silva Cunha, Francisco De Assis Almeida Lima-Júnior, Wilson Déda Gonçalves Júnior, Thiago De Santana Santos, Ericka Janine Dantas Da Silveira, Silvia Ferreira De Sousa, Ricardo Luiz Cavalcanti De Albuquerque-Júnior

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

John Lennon Silva CunhaLaboratory of Morphology and Experimental Pathology, Institute of Technology and Research, Tiradentes University, Av. Murilo Dantas, 300, Farolândia, Aracaju, SE, 49032-490, Brazil. lennonrrr@live.com.ORCID http://orcid.org/0000-0002-0679-8485
Francisco De Assis Almeida Lima-JúniorDepartment of Dentistry, Tiradentes University, R. Lagarto, 264, Centro, Aracaju, SE, 49010-390, Brazil.
Wilson Déda Gonçalves JúniorDepartment of Dentistry, Tiradentes University, R. Lagarto, 264, Centro, Aracaju, SE, 49010-390, Brazil.
Thiago De Santana SantosDepartment of Dentistry, Tiradentes University, R. Lagarto, 264, Centro, Aracaju, SE, 49010-390, Brazil.
Ericka Janine Dantas Da SilveiraDepartment of Dentistry, Postgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Av. Sen. Salgado Filho, 1787, Lagoa Nova, Natal, RN, 59056-000, Brazil.
Silvia Ferreira De SousaDepartment of Dentistry, Federal University of Sergipe, R. Cláudio Batista, Cidade Nova, Aracaju, SE, 49060-108, Brazil.
Ricardo Luiz Cavalcanti De Albuquerque-JúniorLaboratory of Morphology and Experimental Pathology, Institute of Technology and Research, Tiradentes University, Av. Murilo Dantas, 300, Farolândia, Aracaju, SE, 49032-490, Brazil.
Universidade Tiradentes · BRInstituto de Tecnologia e Pesquisa · BRUniversidade Federal de Sergipe · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhabdomyosarcoma (RMS) is a rare oral malignant soft tissue tumor whose pathological features may influence the clinical behavior, treatment and prognosis of the lesion. We report a case of a 13-year-old female patient, presenting an asymptomatic polypoid swelling in the left buccal mucosa that was approximately 2.5 cm in diameter and 3 months evolution. The presumptive diagnosis was fibrous hyperplasia and an excisional biopsy was carried out. Pathologic analysis revealed proliferation of predominantly ovoid cells, with eosinophilic cytoplasm and pleomorphic nuclei, arranged in subepithelial cambium layer. The mucosal surface presented a papillary-verrucous appearance. Immunohistochemical analysis revealed intense positivity for desmin, myogenin and Ki-67. The diagnosis was of embryonal RMS (botryoid variant). The patient was subjected to complementary chemotherapy and radiotherapy, with no evidence of recurrence or metastatic disease after 12 months follow-up. A discussion on the clinical, histopathological, immunohistochemical and therapeutic aspects of botryoid RMS will be provided.

Indexed as

AdolescentFemaleHumansMouth MucosaMouth NeoplasmsRhabdomyosarcoma, EmbryonalHead and neck neoplasmsPediatric rhabdomyosarcomaRadiotherapyRhabdomyosarcoma

Identifiers

PMID30094776
PMCPMC6854166
OpenAlexW2885276726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.