ArticleBrain structure & function2018
Interactive histogenesis of axonal strata and proliferative zones in the human fetal cerebral wall.
Article in Brain structure & function, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Iron Deficiency Impairs Mitochondrial Energetics and Early Axonal Growth and Branching in Developing Hippocampal Neurons.The Journal of nutrition · 2026Article
- Transcriptomic divergence of network hubs in the prenatal human brain.Communications biology · 2025Article
- White Matter Tract Crossing and Bottleneck Regions in the Fetal Brain.Human brain mapping · 2025Article
- Initial regional cytoarchitectonic differences in dorsal and orbitobasal human developing frontal cortex revealed by spatial transcriptomics.Brain structure & function · 2024Article
- Development of the basic architecture of neocortical circuitry in the human fetus as revealed by the coupling spatiotemporal pattern of synaptogenesis along with microstructure and macroscale in vivo MR imaging.Brain structure & function · 2024Article
- White matter tract crossing and bottleneck regions in the fetal brain.bioRxiv : the preprint server for biology · 2024Article
- Correlation between the number of interstitial neurons of the white matter and number of neurons within cortical layers: Histological analyses in postnatal macaque.The Journal of comparative neurology · 2024Article
- Neurogenesis in primates versus rodents and the value of non-human primate models.National science review · 2023Review
- Geodesic theory of long association fibers arrangement in the human fetal cortex.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The HOPX and BLBP landscape and gliogenic regions in developing human brain.Journal of anatomy · 2023Article
- Fetal MRI based brain atlas analysis detects initial in utero effects of prenatal alcohol exposure.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Laminar dynamics of deep projection neurons and mode of subplate formation are hallmarks of histogenetic subdivisions of the human cingulate cortex before onset of arealization.Brain structure & function · 2023Article
- Article
- Article
- Coordinating cerebral cortical construction and connectivity: Unifying influence of radial progenitors.Neuron · 2022Review
- Structural Changes in the Cortico-Ponto-Cerebellar Axis at Birth are Associated with Abnormal Neurological Outcomes in Childhood.Clinical neuroradiology · 2021Article
- Human intermediate progenitor diversity during cortical development.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Fundamentals of the Development of Connectivity in the Human Fetal Brain in Late Gestation: From 24 Weeks Gestational Age to Term.Journal of neuropathology and experimental neurology · 2021Article
- Spatiotemporal Differences in the Regional Cortical Plate and Subplate Volume Growth during Fetal Development.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Quantitative In vivo MRI Assessment of Structural Asymmetries and Sexual Dimorphism of Transient Fetal Compartments in the Human Brain.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
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6 authors.
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Abstract
Development of the cerebral wall is characterized by partially overlapping histogenetic events. However, little is known with regards to when, where, and how growing axonal pathways interact with progenitor cell lineages in the proliferative zones of the human fetal cerebrum. We analyzed the developmental continuity and spatial distribution of the axonal sagittal strata (SS) and their relationship with proliferative zones in a series of human brains (8-40 post-conceptional weeks; PCW) by comparing histological, histochemical, and immunocytochemical data with magnetic resonance imaging (MRI). Between 8.5 and 11 PCW, thalamocortical fibers from the intermediate zone (IZ) were initially dispersed throughout the subventricular zone (SVZ), while sizeable axonal "invasion" occurred between 12.5 and 15 PCW followed by callosal fibers which "delaminated" the ventricular zone-inner SVZ from the outer SVZ (OSVZ). During midgestation, the SS extensively invaded the OSVZ, separating cell bands, and a new multilaminar axonal-cellular compartment (MACC) was formed. Preterm period reveals increased complexity of the MACC in terms of glial architecture and the thinning of proliferative bands. The addition of associative fibers and the formation of the centrum semiovale separated the SS from the subplate. In vivo MRI of the occipital SS indicates a "triplet" structure of alternating hypointense and hyperintense bands. Our results highlighted the developmental continuity of sagittally oriented "corridors" of projection, commissural and associative fibers, and histogenetic interaction with progenitors, neurons, and glia. Histogenetical changes in the MACC, and consequently, delineation of the SS on MRI, may serve as a relevant indicator of white matter microstructural integrity in the developing brain.
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