ArticleParasitology research2018
Contact lens-related polymicrobial keratitis: Acanthamoeba spp. genotype T4 and Candida albicans.
Article in Parasitology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- A history of over 40 years of potentially pathogenic free-living amoeba studies in Brazil - a systematic review.Memorias do Instituto Oswaldo Cruz · 2022Pooled it
- Genotype distribution of Acanthamoeba in keratitis: a systematic review.Parasitology research · 2021Pooled it
- Evaluation of Adhesion and Co-culture Efficacy Assays of Antifungals and Chlorhexidine Against Acanthamoeba and Candida Species Associated with Severe Infectious Keratitis.Current microbiology · 2026Article
- Interactions of the emerging fungusMicrobiology spectrum · 2025Article
- Clinical Characteristics and In Vivo Confocal Microscopic Study in Candida Keratitis.Translational vision science & technology · 2025Article
- Anti-Acanthamoeba metallopharmaceuticals: Amoebicidal activity and synergistic effect of copper(II) coordination compound.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Article
- New Frontiers inBiology · 2023Review
- Candidacidal and Antibiofilm Activity of PS1-3 Peptide against Drug-ResistantPharmaceutics · 2022Article
- Chlorhexidine for the Treatment ofJournal of fungi (Basel, Switzerland) · 2021Article
- Detection and Identification ofJournal of clinical microbiology · 2021Article
- Three Decades of Contact Lens-associated Microbial Keratitis in a Referral Hospital in São Paulo, Brazil.Arquivos brasileiros de oftalmologia · 2021Article
- Multifunctional Monoclonal Antibody TargetingVaccines · 2020Article
- Molecular characterization of theInfection and drug resistance · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 31-year-old female daily user of contact lenses sought medical attention, reporting blurred vision and irritation of the left eye. Slit-lamp examination revealed hyperemia and an irregular corneal epithelium surface, and empirical treatment was started. A corneal scrape was obtained and examined for the presence of fungi, bacteria, and Acanthamoeba spp. The results of the microbial culture revealed growth of Acanthamoeba spp. and Candida albicans. The Acanthamoeba isolate was characterized by cyst morphology as belonging to group II according to Pussard and Pons. Sequencing of the diagnostic fragment 3 (DF3) region located on the 18S ribosomal DNA identified the isolate as genotype T4. The patient was treated with chlorhexidine 0.02% and polyhexamethylene biguanide (PHMB) 0.02% drops for 5 months until the infection resolved. Lately, rare cases of polymicrobial keratitis associated with Acanthamoeba and Candida albicans have been reported. Cases of co-infection are more difficult to treat, since the specific treatment depends on precise identification of the agents involved.
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Registered trials
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