Evidence map›Paper›PMID 30094536›Full record

ReviewJournal of cancer research and clinical oncology2018

Melanoma treatment: from conventional to nanotechnology.

Harshita Mishra, Pawan K Mishra, Adam Ekielski, Manu Jaggi, Zeenat Iqbal, Sushama Talegaonkar

Abstract readReview
In one paragraph

Review in Journal of cancer research and clinical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. FeNanomaterials (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Nanotechnology as a Promising Method in the Treatment of Skin Cancer.International journal of molecular sciences · 2024
    Review
  20. Ruthenium(II) complex with 2-mercaptothiazoline ligand induces selective cytotoxicity involving DNA damage and apoptosis in melanoma cells.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Harshita MishraSchool of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Pawan K MishraDepartment of Wood Processing Technologies, Mendel University in Brno, Brno, Czech Republic.
Adam EkielskiDepartment of Production Management and Engineering, Faculty of Production Engineering, Warsaw University of Life Sciences, Warsaw, Poland.
Manu JaggiDabur Research Foundation, Ghaziabad, India.
Zeenat IqbalSchool of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Sushama TalegaonkarSchool of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. stalegaonkar@jamiahamdard.ac.in.ORCID http://orcid.org/0000-0001-5301-5298

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMelanoma is the most serious form of skin cancer causing most of the skin cancer-related deaths. The incidence of melanoma has risen so dramatically over past few years that no other solid or blood malignancy comes close to it in terms of increased incidence. The main problem associated with the treatment of melanoma is low response rate to the existing treatment modalities, which in turn is due to the incomplete response by chemotherapeutic agents and inherent resistance of melanoma cells. MATERIALS AND

methodsConventional therapeutic strategies, as well as, recent literature on melanoma have been thoroughly studied. This review summarizes the base of anti-melanoma treatment with conventional chemotherapeutic drugs, followed by an account of recent studies which explored the potential of nanotechnology and newer strategies and agents in melanoma treatment.

conclusionAlthough melanoma is curable if detected in its early localized form, metastatic melanoma continues to be a therapeutic challenge. Metastatic melanoma has a very poor prognosis and conventional therapies have not improved the outcomes of the treatment so far. For this reason, newer combinations of anti-melanoma drugs and newer strategies utilizing nanotechnology have been constantly explored.

Indexed as

AnimalsBiomarkers, TumorCombined Modality TherapyDisease ManagementDrug DiscoveryHumansMelanomaNanomedicineNanotechnologyStandard of CareBiomarkers, TumorAnti-melanomaDacarbazineImmuno-therapyMelanoma treatmentNano-agentsNanotechnologyTargeted therapy

Identifiers

PMID30094536
PMCPMC11813321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.