Evidence map›Paper›PMID 30094460›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Radiomics analysis of pre-treatment [

E J van Helden, Y J L Vacher, W N van Wieringen, F H P van Velden, H M W Verheul, O S Hoekstra, R Boellaard, C W Menke-van der Houven van Oordt

Registry-linked trialAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04276025 (Relationship Between Histopathological Features, Mutation Status, 18F-FDG PET/CT Radiomic Imaging Parameters as Well as Clinical Outcome in Patients With Treatment-naïve Non-small Cell Lung Cancer), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04276025 completednot on this map

Relationship Between Histopathological Features, Mutation Status, 18F-FDG PET/CT Radiomic Imaging Parameters as Well as Clinical Outcome in Patients With Treatment-naïve Non-small Cell Lung Cancer

TypeobservationalSponsorKlinikum Bayreuth GmbHRan2016 to 2020Enrolled2,000ConditionsNSCLCArmsClinical routine F18-FDG-PET/CT, molecular pathology and clinical outcome
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Development and Validation of anJCO clinical cancer informatics · 2025
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  9. The prognostic value of [Clinical physiology and functional imaging · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

E J van HeldenCancer Center Amsterdam, Department of Medical Oncology, VUmc, Amsterdam, the Netherlands.
Y J L VacherCancer Center Amsterdam, Department of Medical Oncology, VUmc, Amsterdam, the Netherlands.
W N van WieringenDepartment of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands.
F H P van VeldenDepartment of Radiology, Section of Nuclear Medicine, Leiden University Medical Center, Leiden, the Netherlands.
H M W VerheulCancer Center Amsterdam, Department of Medical Oncology, VUmc, Amsterdam, the Netherlands.
O S HoekstraDepartment of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.
R BoellaardDepartment of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.
C W Menke-van der Houven van OordtCancer Center Amsterdam, Department of Medical Oncology, VUmc, Amsterdam, the Netherlands. c.menke@vumc.nl.ORCID http://orcid.org/0000-0002-5404-5883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to assess radiomics features on pre-treatment [

methodsPatients with mCRC underwent [

resultsLesions of 47 patients receiving third-line systemic treatment had higher SUV

conclusionWe demonstrated an association between improved clinical outcome and pre-treatment low tumour volume and heterogeneity as well as high sphericity on [

Indexed as

Fluorodeoxyglucose F18Image Processing, Computer-AssistedPalliative CarePositron Emission Tomography Computed TomographyAdultAgedAged, 80 and overColonic NeoplasmsDisease-Free SurvivalFemaleHumansMaleMiddle AgedNeoplasm MetastasisRetrospective StudiesTumor BurdenFluorodeoxyglucose F18[18F]FDG PET/CTBiomarkerColorectal cancerRadiomicsRetrospective clinical trialTumour heterogeneity

Identifiers

PMID30094460
PMCPMC6208805

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.