ReviewFrontiers in bioengineering and biotechnology2018
Skin Tissue Substitutes and Biomaterial Risk Assessment and Testing.
Review in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Skin Substitutes for Adults With Diabetic Foot Ulcers and Venous Leg Ulcers: A Health Technology Assessment.Ontario health technology assessment series · 2021Pooled it
- Dermal Templates Support Epidermal Regeneration and Maturation Regardless of Cell Donor Age.Tissue engineering. Part A · 2026Article
- Skin Relevant Biomaterials from Wound Healing, Medical Aesthetics, Flexible Electronics to Artificial Intelligence and Beyond.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Study protocol and statistical analysis plan for a randomized, double-blind, controlled trial evaluating recombinant human platelet-derived growth factor B (rhPDGF) in the reconstruction of complex head or neck defects following skin cancer excision.medRxiv : the preprint server for health sciences · 2026Article
- Engineered atopic dermatitis models for recreating hypoxic conditions in atopic dermatitis microenvironments.Bioactive materials · 2026Article
- A Novel Sprayable Fibrinogen/Glycosaminoglycans/Collagen-Based Bioink for Skin Wound Healing Applied by a Handheld Dual-Head Airbrush.Advanced healthcare materials · 2026Article
- Translational Extracellular Matrix Spray-Coating Approach for Large-Scale Bioactive Surface Functionalization and Tissue Repair.Advanced healthcare materials · 2025Article
- Use of a Novel Application Technique of MatriDerm to Improve Handling and Ease.Plastic and reconstructive surgery. Global open · 2025Article
- Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration.Advanced healthcare materials · 2025Article
- Low molecular weight fucoidan differentiation media enhances quality and extents shelf life of 3D human skin model.Scientific reports · 2025Article
- Three-Dimensional Bioprinting Techniques in Skin Regeneration: Current Insights and Future Perspectives.Life (Basel, Switzerland) · 2025Review
- Multilayer Antibacterial Hydrogel Wound Dressings Incorporated With Green Synthesized Silver Nanoparticles.Drug development research · 2025Article
- Microstructural Effects of Melt Electrowritten-Reinforced Hydrogel Scaffolds for Engineering Thick Skin Substitutes.ACS applied bio materials · 2025Article
- Cellulose-Based Nanofibers Infused with Biotherapeutics for Enhanced Wound-Healing Applications.ACS polymers Au · 2025Review
- Enhanced Cell Proliferation, Migration, and Fibroblast Differentiation with Electrospun PCL-Zinc Scaffolds Coated with Fibroblast-Derived ECM.ACS omega · 2025Article
- Synthesis and Characterization of a Pla Scaffold with Pseudoboehmite and Graphene Oxide Nanofillers Added.Nanomaterials (Basel, Switzerland) · 2025Article
- Arginine-Biofunctionalized Ternary Hydrogel Scaffolds of Carboxymethyl Cellulose-Chitosan-Polyvinyl Alcohol to Deliver Cell Therapy for Wound Healing.Gels (Basel, Switzerland) · 2024Article
- The Impact of Temperature and the Duration of Freezing on a Hydrogel Used for a 3D-Bioprinted In Vitro Skin Model.Biomedicines · 2024Article
- COMPARATIVE STUDY OF STRIPED CATFISHAnnals of burns and fire disasters · 2024Article
- Current Knowledge and Perspectives of Phage Therapy for Combating Refractory Wound Infections.International journal of molecular sciences · 2024Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tremendous progress has been made over the past few decades to develop skin substitutes for the management of acute and chronic wounds. With the advent of tissue engineering and the ability to combine advanced manufacturing technologies with biomaterials and cell culture systems, more biomimetic tissue constructs have been emerged. Synthetic and natural biomaterials are the main constituents of these skin-like constructs, which play a significant role in tissue grafting, the body's immune response, and the healing process. The act of implanting biomaterials into the human body is subject to the body's immune response, and the complex nature of the immune system involves many different cell types and biological processes that will ultimately determine the success of a skin graft. As such, a large body of recent studies has been focused on the evaluation of the performance and risk assessment of these substitutes. This review summarizes the past and present advances in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.