ArticleNeuroImage. Clinical2018
Type and timing of childhood maltreatment and reduced visual cortex volume in children and adolescents with reactive attachment disorder.
Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Neurostructural traces of early life adversities: A meta-analysis exploring age- and adversity-specific effects.Neuroscience and biobehavioral reviews · 2022Pooled it
- Associations of childhood maltreatment types and timing with oxidative stress in formerly out-of-home placed young adults.European journal of psychotraumatology · 2026Article
- Exploring the mediating role of functional connectivity in the association between violence exposure and psychopathology during early adolescence.Brain and cognition · 2026Article
- Childhood Adversity and Reactive Attachment Disorder in Adolescents: A Systematic Review.Journal of child & adolescent trauma · 2026Article
- Hearing and early life adversity: effects of developmental stress on sensory processing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- The neurobiological effects of childhood maltreatment on brain structure, function, and attachment.European archives of psychiatry and clinical neuroscience · 2025Review
- Adverse Childhood Experiences (ACEs) in Specific Vulnerable Developmental Periods Can Increase the Likelihood of Chronic Pain in Adulthood-Results from a Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Assessing childhood maltreatment exposure using the child behavior checklist.Frontiers in child and adolescent psychiatry · 2025Article
- Subclinical structural atypicality of retinal thickness and its association with gray matter volume in the visual cortex of maltreated children.Scientific reports · 2024Article
- Impact of Stress on Brain Morphology: Insights into Structural Biomarkers of Stress-related Disorders.Current neuropharmacology · 2024Review
- Corticotropin releasing factor neurons in the visual cortex mediate long-term changes in visual function induced by early adversity.Neurobiology of stress · 2022Article
- Trauma in Context: an Integrative Treatment Model.Journal of child & adolescent trauma · 2022Article
- A meta-analysis of brain morphometric aberrations in adolescents who experienced childhood trauma.Frontiers in human neuroscience · 2022Article
- Effects of intranasal oxytocin on neural reward processing in children and adolescents with reactive attachment disorder: A randomized controlled trial.Frontiers in child and adolescent psychiatry · 2022Article
- A multi-modal MRI analysis of brain structure and function in relation to OXT methylation in maltreated children and adolescents.Translational psychiatry · 2021Article
- A sex-dependent delayed maturation of visual plasticity induced by adverse experiences in early childhood.Neurobiology of stress · 2020Article
- The type of stress matters: repeated injection and permanent social isolation stress in male mice have a differential effect on anxiety- and depressive-like behaviours, and associated biological alterations.Translational psychiatry · 2020Article
- Development of Social Attention and Oxytocin Levels in Maltreated Children.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive attachment disorder (RAD) is a severe social functioning disorder associated with early childhood maltreatment where the child displays emotionally withdrawn/inhibited behaviors toward caregivers. Brain regions develop at different rates and regions undergoing rapid change may be particularly vulnerable during these times to stressors or adverse experiences. The aim of this study was to investigate the effect of type and timing of childhood adversities on structural alterations in regional gray matter (GM) volume in maltreated children with RAD. High-resolution magnetic resonance imaging datasets were obtained for children and adolescents with RAD (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.