Evidence map›Paper›PMID 30094088›Full record

ReviewAmerican journal of cancer research2018

The animal nuclear factor Y: an enigmatic and important heterotrimeric transcription factor.

Guilin Li, Hang Zhao, Lijun Wang, Ying Wang, Xingqi Guo, Baohua Xu

Open access · greenAbstract readReview
In one paragraph

Review in American journal of cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Climate change-induced stress in the honey beeFrontiers in physiology · 2025
    Review
  7. Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  8. Article
  9. Article
  10. Cell Cycle Regulation by NF-YC inInternational journal of molecular sciences · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Transcriptional regulation of the porcine miR-17-92 cluster.Molecular genetics and genomics : MGG · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guilin LiState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University Taian 271018, Shandong, P. R. China.
Hang ZhaoState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University Taian 271018, Shandong, P. R. China.
Lijun WangState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University Taian 271018, Shandong, P. R. China.
Ying WangCollege of Animal Science and Technology, Shandong Agricultural University Taian 271018, Shandong, P. R. China.
Xingqi GuoState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University Taian 271018, Shandong, P. R. China.
Baohua XuCollege of Animal Science and Technology, Shandong Agricultural University Taian 271018, Shandong, P. R. China.
Shandong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear factor Y (NF-Y) is a heterotrimeric transcription factor with the ability to bind to CCAAT boxes in nearly all eukaryotes and has long been a topic of interest since it is first identified. In plants, due to each subunit of NF-Y is encoded by multiple gene families, there are a wide variety NF-Y complex combinations that fulfill many pivotal functions. However, the animal NF-Y complex usually has only one type of combination, as each subunit is generally encoded by a single gene. Even though, mounting evidence points to that the animal NF-Y complex is also essential for numerous biological processes involved in proliferation and apoptosis, cancer and tumor, stress responses, growth and development. Therefore, a relatively comprehensive functional dissection of animal NF-Y will enable a deeper comprehension of how lesser combinations of the NF-Y complex regulate diverse aspects of biology processes in animal. Here, we focus mainly on reviewing recent advances related to NF-Y in the animal field, including subunit structural characteristics, expression regulation models and biological functions, and we also discuss future directions.

Indexed as

cancer and tumorexpression regulation modelgrowth and developmentNuclear factor Yproliferation and apoptosisstress response

Identifiers

PMID30094088
PMCPMC6079162
OpenAlexW2989438778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.