Evidence map›Paper›PMID 30094086›Full record

ReviewJournal of advanced research2018

Schiff bases and their metal complexes as urease inhibitors - A brief review.

Ângelo de Fátima, Camila de Paula Pereira, Carolina Raquel Said Dau Gonçalves Olímpio, Breno Germano de Freitas Oliveira, Lucas Lopardi Franco, Pedro Henrique Corrêa da Silva

Open access · goldAbstract readReview
In one paragraph

Review in Journal of advanced research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 167 citations in OpenAlex.

  1. Article
  2. Ni(II) Complexes with Mixed Ligands, Reduced NInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Anthracene scaffold as highly selective chemosensor for AlPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  12. Review
  13. Equilibria of complexes in the aqueous cobalt(II)-Computational and structural biotechnology journal · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ângelo de FátimaDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Camila de Paula PereiraDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Carolina Raquel Said Dau Gonçalves OlímpioDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Breno Germano de Freitas OliveiraDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Lucas Lopardi FrancoDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Pedro Henrique Corrêa da SilvaDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Universidade Federal de Minas Gerais · BRUniversidade Federal de Alfenas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schiff bases, an aldehyde- or ketone-like compounds in which the carbonyl group is replaced by an imine or azomethine, are some of the most widely used organic compounds. Indeed, they are widely used for industrial purposes and also exhibit a broad range of biological activities, including anti-urease activity. Ureases, enzymes that catalyze urea hydrolysis, have received considerable attention for their impact on living organisms' health, since the persistence of urease activity in human and animal cells can be the cause of some diseases and pathogen infections. This short review compiles examples of the most antiurease Schiff bases (0.23 μM < IC

Indexed as

Canavalia ensiformisHelicobacter pyloriMetal complexSchiff baseUreaUreaseUrease inhibitor

Identifiers

PMID30094086
PMCPMC6077242
OpenAlexW2791370528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.