Evidence map›Paper›PMID 30093904›Full record

ReviewFrontiers in immunology2018

Inhibition of Lipopolysaccharide- and Lipoprotein-Induced Inflammation by Antitoxin Peptide Pep19-2.5.

Lena Heinbockel, Günther Weindl, Guillermo Martinez-de-Tejada, Wilmar Correa, Susana Sanchez-Gomez, Sergio Bárcena-Varela, Torsten Goldmann, Patrick Garidel, Thomas Gutsmann, Klaus Brandenburg

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
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  12. Dental Stem Cells and Lipopolysaccharides: A Concise Review.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Lena HeinbockelClinical and Experimental Pathology, Research Center Borstel, Borstel, Germany.
Günther WeindlInstitute of Pharmacy (Pharmacology and Toxicology), Freie Universität Berlin, Berlin, Germany.
Guillermo Martinez-de-TejadaDepartment of Microbiology and Parasitology, Universidad de Navarra, Pamplona, Spain.
Wilmar CorreaBiophysics, Research Center Borstel, Borstel, Germany.
Susana Sanchez-GomezDepartment of Microbiology and Parasitology, Universidad de Navarra, Pamplona, Spain.
Sergio Bárcena-VarelaDepartment of Microbiology and Parasitology, Universidad de Navarra, Pamplona, Spain.
Torsten GoldmannClinical and Experimental Pathology, Research Center Borstel, Borstel, Germany.
Patrick GaridelMartin-Luther Universität Halle-Wittenberg, Halle, Germany.
Thomas GutsmannBiophysics, Research Center Borstel, Borstel, Germany.
Klaus BrandenburgBiophysics, Research Center Borstel, Borstel, Germany.
Research Center Borstel - Leibniz Lung Center · DEUniversidad de Navarra · ESFreie Universität Berlin · DEMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most potent cell wall-derived inflammatory toxins ("pathogenicity factors") of Gram-negative and -positive bacteria are lipopolysaccharides (LPS) (endotoxins) and lipoproteins (LP), respectively. Despite the fact that the former signals

Indexed as

AnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntimicrobial Cationic PeptidesEndotoxinsHumansInflammationLipopolysaccharidesLipoproteinsPeptidesAnti-Bacterial AgentsAnti-Inflammatory AgentsAntimicrobial Cationic PeptidesEndotoxinsLipopolysaccharidesLipoproteinsPep19-2.5 peptidePeptidesantimicrobial peptidesendotoxinintracellular LPS signalingPep19-2.5sepsis

Identifiers

PMID30093904
PMCPMC6070603
OpenAlexW2883186768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.