ArticleScientific reports2018
A nuclear-encoded protein, mTERF6, mediates transcription termination of rpoA polycistron for plastid-encoded RNA polymerase-dependent chloroplast gene expression and chloroplast development.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 64 citations in OpenAlex.
- Review
- Lineage-specific expansion and functional diversification of mTERF proteins sculpt organellar regulation in plants.BMC plant biology · 2026Article
- Genome-Wide Identification and Characterization of the mTERF Gene Family in Spinach and the Role ofPlants (Basel, Switzerland) · 2025Article
- Historical biogeography and plastome evolution of Commelinaceae Mirb. (Commelinales) corroborate the East Gondwanan origins.BMC plant biology · 2025Article
- Mapping of identity by descent reveals genes shaping morphology and biological traits in the cultivated lettuce varieties during the long-term crossbreeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Characterization of the DNA accessibility of chloroplast genomes in grasses.Communications biology · 2024Article
- Light response of gametophyte inFrontiers in plant science · 2023Article
- Plastid Deficient 1 Is Essential for the Accumulation of Plastid-Encoded RNA Polymerase Core Subunit β and Chloroplast Development inInternational journal of molecular sciences · 2021Article
- A rice mTERF protein V14 sustains photosynthesis establishment and temperature acclimation in early seedling leaves.BMC plant biology · 2021Article
- Arabidopsis Mitochondrial Transcription Termination Factor mTERF2 Promotes Splicing of Group IIB Introns.Cells · 2021Article
- Mitochondrial Transcription Termination Factor 27 Is Required for Salt Tolerance inInternational journal of molecular sciences · 2021Article
- Arabidopsis mTERF9 protein promotes chloroplast ribosomal assembly and translation by establishing ribonucleoprotein interactions in vivo.Nucleic acids research · 2021Article
- Review
- A Novel Chloroplast Protein RNA Processing 8 Is Required for the Expression of Chloroplast Genes and Chloroplast Development inFrontiers in plant science · 2021Article
- Identification, Characterization, and Expression Profile Analysis of theFrontiers in plant science · 2021Article
- Chloroplast Genome Evolution in Four Montane Zingiberaceae Taxa in China.Frontiers in plant science · 2021Article
- The Arabidopsis mTERF-repeat MDA1 protein plays a dual function in transcription and stabilization of specific chloroplast transcripts within the psbE and ndhH operons.The New phytologist · 2020Article
- Arabidopsis Plastid-RNA Polymerase RPOTp Is Involved in Abiotic Stress Tolerance.Plants (Basel, Switzerland) · 2020Article
- Plastid genomics ofPeerJ · 2020Article
- Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
The expression of plastid genes is regulated by two types of DNA-dependent RNA polymerases, plastid-encoded RNA polymerase (PEP) and nuclear-encoded RNA polymerase (NEP). The plastid rpoA polycistron encodes a series of essential chloroplast ribosome subunits and a core subunit of PEP. Despite the functional importance, little is known about the regulation of rpoA polycistron. In this work, we show that mTERF6 directly associates with a 3'-end sequence of rpoA polycistron in vitro and in vivo, and that absence of mTERF6 promotes read-through transcription at this site, indicating that mTERF6 acts as a factor required for termination of plastid genes' transcription in vivo. In addition, the transcriptions of some essential ribosome subunits encoded by rpoA polycistron and PEP-dependent plastid genes are reduced in the mterf6 knockout mutant. RpoA, a PEP core subunit, accumulates to about 50% that of the wild type in the mutant, where early chloroplast development is impaired. Overall, our functional analyses of mTERF6 provide evidence that it is more likely a factor required for transcription termination of rpoA polycistron, which is essential for chloroplast gene expression and chloroplast development.
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