Evidence map›Paper›PMID 30093662›Full record

ArticleScientific reports2018

A simple and inexpensive quantitative technique for determining chemical sensitivity in Saccharomyces cerevisiae.

Chao-Wei Hung, Jorge Y Martínez-Márquez, Fatima T Javed, Mara C Duncan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

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  8. Identifying Drug Sensitivities in Fission Yeast by Assessing Growth Kinetics.Methods in molecular biology (Clifton, N.J.) · 2025
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  14. Analysis of the Plasmid-BasedMicrobiology spectrum · 2023
    Article
  15. Article
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  18. Analysis of the Plasmid-BasedApplied and environmental microbiology · 2022
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chao-Wei HungDepartment of Biology, University of North Carolina, Chapel Hill, North Carolina, USA. c7hung@ucsd.edu.ORCID 0000-0003-2365-9716
Jorge Y Martínez-MárquezDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-1485-4800
Fatima T JavedDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Mara C DuncanDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan · USUniversity of North Carolina at Chapel Hill · US

Funding

Regulatory mechanisms of clathrin dependant traffic at the TGN and endosomesR01GM092741 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DUNCAN, MARA C · 2011 to 2015
$1.4M
The regulation of glucose starvation-induced cell surface protein clearance in yeastF31GM112470 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARTINEZ-MARQUEZ, JORGE YAMIL · 2015 to 2016
$68k
NIGMS NIH HHS F31 GM112470NIGMS NIH HHS R01 GM092741
6 · The paper itself

Abstract

Chemical sensitivity, growth inhibition in response to a chemical, is a powerful phenotype that can reveal insight into diverse cellular processes. Chemical sensitivity assays are used in nearly every model system, however the yeast Saccharomyces cerevisiae provides a particularly powerful platform for discovery and mechanistic insight from chemical sensitivity assays. Here we describe a simple and inexpensive approach to determine chemical sensitivity quantitatively in yeast in the form of half maximal inhibitory concentration (IC

Indexed as

BenzenesulfonatesBiological AssayCell MembraneCost-Benefit AnalysisEndosomesInhibitory Concentration 50Protein TransportReproducibility of ResultsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTime Factorstrans-Golgi NetworkBenzenesulfonatesC.I. Fluorescent Brightening Agent 28Saccharomyces cerevisiae Proteins

Identifiers

PMID30093662
PMCPMC6085351
OpenAlexW2886273206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.