Evidence map›Paper›PMID 30093217›Full record

ReviewAcademic radiology2019

Current Advances in COPD Imaging.

Jeffrey Thiboutot, Wu Yuan, Hyeon-Cheol Park, Andrew D Lerner, Wayne Mitzner, Lonny B Yarmus, Xingde Li, Robert H Brown

Open access · greenAbstract readReview
In one paragraph

Review in Academic radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  3. Observational
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jeffrey ThiboutotJohns Hopkins University, Department of Medicine, Division of Pulmonary and Critical Care Medicine, 1830 E. Monument St. 5th Floor, Baltimore, MD 21205. Electronic address: jthibou1@jhmi.edu.
Wu YuanJohns Hopkins University, Department of Biomedical Engineering, Baltimore, Maryland.
Hyeon-Cheol ParkJohns Hopkins University, Department of Biomedical Engineering, Baltimore, Maryland.
Andrew D LernerJohns Hopkins University, Department of Medicine, Division of Pulmonary and Critical Care Medicine, 1830 E. Monument St. 5th Floor, Baltimore, MD 21205.
Wayne MitznerJohns Hopkins University, Department of Environmental Health and Engineering, Baltimore, Maryland.
Lonny B YarmusJohns Hopkins University, Department of Medicine, Division of Pulmonary and Critical Care Medicine, 1830 E. Monument St. 5th Floor, Baltimore, MD 21205.
Xingde LiJohns Hopkins University, Department of Biomedical Engineering, Baltimore, Maryland.
Robert H BrownJohns Hopkins University, Department of Anesthesiology and Critical Care Medicine, Medicine, Department of Medicine, Division of Pulmonary Medicine, Department of Environmental Health and Engineering, and Department of Radiology, Baltimore, Maryland.
Johns Hopkins University · US

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease in vivoR01HL121788 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BROWN, ROBERT H, LI, XINGDE · 2014 to 2018
$3.7M
NHLBI NIH HHS R01 HL121788NHLBI NIH HHS T32 HL007534
6 · The paper itself

Abstract

objectiveTo review the recent advances in available technologies for imaging COPD and present the novel optical coherence tomography (OCT) airway imaging technology. MATERIALS AND

methodsThis is an unstructured review of published evidence of available pulmonary imaging technologies along with a demonstration of state-of-the-art OCT imaging technology of in vivo human and animal airways.

resultsAdvanced imaging techniques such as Magnetic Resonance (MR) imaging using hyperoloarized noble gases, micro-Computed Tomography (micro-CT), and OCT aim to further our understanding of COPD. Lung densitometry can aid in identifying an exacerbation prone phenotype which may have implications for targeting specific therapies to these individuals. MR ventilation scans have the ability to provide a functional and regional distribution of airflow obstruction offering insight into the airway and parenchymal changes induced by COPD. Micro-CT gives a near microscopic view of the terminal bronchioles and alveoli permitting study of the microarchitecture of the lung ex vivo. Optical coherence tomography can visualize the microstructure of the airway walls (epithelium, smooth muscle, blood vessels, cartilage) permitting real time in vivo as well as longitudinal evaluation of airway changes in patients with COPD.

conclusionAdvanced imaging techniques play a vital role in expanding our current understanding of COPD.

Indexed as

Tomography, Optical CoherenceX-Ray MicrotomographyAnimalsBronchiolesHumansMagnetic Resonance ImagingPulmonary AlveoliPulmonary Disease, Chronic ObstructiveCOPDOptical coherence tomography

Identifiers

PMID30093217
PMCPMC11247962
OpenAlexW2886462656

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.