Evidence map›Paper›PMID 30092253›Full record

ArticleJournal of molecular biology2018

Biochemical and Structural Insights into an Fe(II)/α-Ketoglutarate/O

Sang Hoon Joo, Charles W Pemble, Eun Gyeong Yang, Christian R H Raetz, Hak Suk Chung

Abstract read
In one paragraph

Article in Journal of molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A ribosomally synthesized and posttranslationally modified peptide with ADP-ribosylation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sang Hoon JooDepartment of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA; Department of Pharmacy, Daegu Catholic University, Gyeongbuk 38430, South Korea.
Charles W PembleDuke Macromolecular Crystallography Center, Duke University Medical Center, Durham, NC 27710, USA; Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
Eun Gyeong YangCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
Christian R H RaetzDepartment of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.
Hak Suk ChungDepartment of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea. Electronic address: hschung@kist.re.kr.

Funding

BIOSYNTHESIS AND FUNCTION OF LIPOPOLYSACCHARIDESR01GM051310 · NIGMS · DUKE UNIVERSITY · PI ZHOU, PEI · 1994 to 2013
$8.1M
NIGMS NIH HHS R01 GM051310
6 · The paper itself

Abstract

During lipopolysaccharide biosynthesis in several pathogens, including Burkholderia and Yersinia, 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) 3-hydroxylase, otherwise referred to as KdoO, converts Kdo to d-glycero-d-talo-oct-2-ulosonic acid (Ko) in an Fe(II)/α-ketoglutarate (α-KG)/O

Indexed as

Models, MolecularAmino Acid SequenceApoproteinsBiochemical PhenomenaDioxygenasesFerrous CompoundsKetoglutaric AcidsMixed Function OxygenasesMolecular StructureOxygenApoproteinsDioxygenasesFerrous CompoundsKetoglutaric AcidsMixed Function OxygenasesOxygendeoxysugar oxidaseFe(II)/α-ketoglutarate/O(2)-dependent dioxygenaseKdo 3-hydroxylase (KdoO)lipopolysaccharide biosynthesisx-ray structure

Identifiers

PMID30092253
PMCPMC6186499

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.