ArticlePloS one2018
Risk of retinal artery occlusion in patients with diabetes mellitus: A retrospective large-scale cohort study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Secondary stroke evaluation in patients admitted for CRAO in a large national inpatient sample.Stroke and vascular neurology · 2026Article
- Central Retinal Artery Occlusion in Acute Care: Current Practices and Emerging Therapies.Cureus · 2025Review
- Retinal Artery Occlusion: A Review of Current Management Practices.Journal of ophthalmic & vision research · 2024Review
- Central retinal artery occlusion: a stroke of the eye.Eye (London, England) · 2024Review
- Ocular Manifestations and Complications of Patent Foramen Ovale: A Narrative Review.Journal of personalized medicine · 2024Review
- The antioxidant, antidiabetic, and antihyperlipidemic effects of the polyphenolic extract from Salvia blancoana subsp. mesatlantica on induced diabetes in rats.Bioresources and bioprocessing · 2024Article
- Causal association of type 2 diabetes with central retinal artery occlusion: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Analysis of the Association between Retinal Artery Occlusion and Acute Ischaemic Stroke/ST-Elevation Myocardial Infarction and Risk Factors in Hungarian Patients.Medicina (Kaunas, Lithuania) · 2023Article
- Review
- The Association between Elevated Hematocrit and Retinal Artery Occlusion in Adult Patients.Journal of clinical medicine · 2022Article
- SARS-CoV-2 infection and diabetes: Pathophysiological mechanism of multi-system organ failure.World journal of virology · 2022Review
- Clinical risk factors for retinal artery occlusions: a nationwide case-control study.International ophthalmology · 2022Article
- Article
- Age, Gender, and Laterality of Retinal Vascular Occlusion: A Retrospective Study from the IRIS® Registry.Ophthalmology. Retina · 2022Article
- Visual field loss in an elderly vasculopath: clinical significance of multimodal imaging.BMJ case reports · 2021Article
- Risk of recurrent corneal erosion in patients with diabetes mellitus in Taiwan: a population-based cohort study.BMJ open · 2020Article
- Correlation of the history of stroke and the retinal artery occlusion: a nested case-control study.International journal of ophthalmology · 2020Article
- Association of elevated circulating GDF15 and risk in acute retinal artery occlusion.Frontiers in neurologyArticle
- Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study.Cardiovascular journal of AfricaArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a globally increasing prevalence and incidence of diabetes mellitus (DM). Prolonged hyperglycaemia could lead to both macrovascular damage, such as carotid artery atherosclerosis, and microvascular damage, such as retinal arteriolar narrowing, and might contribute to retinal artery occlusion (RAO). Accordingly, it is important to determine whether DM is a contrubuting factor of RAO. We conducted a retrospective cohort study that included 241,196 DM patients from the Longitudinal Cohort of Diabetes Patients Database who were recruited between 2003 and 2005. An age- and sex-matched non-DM control group included the same number of patients who were selected from the Taiwan Longitudinal Health Insurance Database of 2000. Relevant data of each patient were collected from the index date until December 2013. The incidence and risk of RAO were calculated and compared between the DM and non-DM groups. The hazard ratio for RAO was calculated using Cox proportional hazards regression analysis after adjusting for confounders. The cumulative incidence rate of RAO was calculated by Kaplan-Meier analysis. In total, 317 patients with DM and 144 controls developed RAO during the follow-up period, leading to an incidence rate of RAO in DM patients that was 2.30 times (95% confidence interval [CI] = 1.89-2.80) greater than that in controls. After adjustment for potential confounders, patients with DM were 2.11 times (95% CI, 1.71-2.59) more likely to develop RAO in the total study cohort. In conclusion, DM increases the risk of RAO, which is an interdisciplinary emergency. Close collaboration between endocrinologists and ophthalmologists is important in managing RAO following DM.
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