ArticleHuman brain mapping2018
Resting-state pulvinar-posterior parietal decoupling in PTSD and its dissociative subtype.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Effects of a dissociative drug on fronto-limbic resting-state functional connectivity in individuals with posttraumatic stress disorder: a randomized controlled pilot study.Psychopharmacology · 2024Trial
- Functional brain imaging in posttraumatic stress disorder: a review.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Body-based therapies and transcranial magnetic stimulation for posttraumatic stress disorder: a proposed integrative approach.Frontiers in psychiatry · 2026Review
- Disrupted thalamocortical functional connectivity and canonical resting-state network integration in posttraumatic stress disorder.NeuroImage. Clinical · 2026Article
- Resilience or vulnerability? thalamic subdivision connectivity in trauma-exposed individuals: a 7 t resting-state fMRI study.Translational psychiatry · 2025Article
- Neural correlates of PTSD in women with childhood sexual abuse with and without PTSD and response to paroxetine treatment: A placebo-controlled, double-blind trial.Journal of affective disorders reports · 2023Article
- Altered Resting-State functional connectivity in the anterior and posterior hippocampus in Post-traumatic stress disorder: The central role of the anterior hippocampus.NeuroImage. Clinical · 2023Article
- Neural correlates of acute post-traumatic dissociation: a functional neuroimaging script-driven imagery study.BJPsych open · 2022Article
- Case Report: Atonic PNES Capture in fMRI.Frontiers in neurology · 2022Article
- The brain-body disconnect: A somatic sensory basis for trauma-related disorders.Frontiers in neuroscience · 2022Review
- Contrasting Associations Between Heart Rate Variability and Brainstem-Limbic Connectivity in Posttraumatic Stress Disorder and Its Dissociative Subtype: A Pilot Study.Frontiers in behavioral neuroscience · 2022Article
- A causal role for the pulvinar in coordinating task-independent cortico-cortical interactions.The Journal of comparative neurology · 2021Article
- The Role of the Thalamus in Post-Traumatic Stress Disorder.International journal of molecular sciences · 2021Review
- How Processing of Sensory Information From the Internal and External Worlds Shape the Perception and Engagement With the World in the Aftermath of Trauma: Implications for PTSD.Frontiers in neuroscience · 2021Review
- Inter-channel phase differences during sleep spindles are altered in Veterans with PTSD.NeuroImage. Clinical · 2020Article
- Emotion Regulation in Essential Hypertension: Roles of Anxiety, Stress, and the Pulvinar.Frontiers in behavioral neuroscience · 2020Article
- Classifying heterogeneous presentations of PTSD via the default mode, central executive, and salience networks with machine learning.NeuroImage. Clinical · 2020Article
- Prevalence and clinical correlates of dissociative subtype of posttraumatic stress disorder at an outpatient trauma clinic in South Korea.European journal of psychotraumatology · 2019Article
- Resting-state pulvinar-posterior parietal decoupling in PTSD and its dissociative subtype.Human brain mapping · 2018Article
- Back to the Basics: Resting State Functional Connectivity of the Reticular Activation System in PTSD and its Dissociative Subtype.Chronic stress (Thousand Oaks, Calif.)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Key evidence points toward alterations in the neurocircuitry of large-scale networks among patients with posttraumatic stress disorder (PTSD). The pulvinar is a thalamic region displaying reciprocal connectivity with the cortex and has been shown to modulate alpha synchrony to facilitate network communication. During rest, the pulvinar displays functional connectivity with the posterior parietal cortex (PPC), a heteromodal network of brain areas underlying multisensory integration and socioaffective functions that are shown at deficit in PTSD. Accordingly, this study seeks to reveal the resting-state functional connectivity (rsFC) patterns of individuals with PTSD, its dissociative subtype (PTSD + DS) and healthy controls. A whole-brain rsFC analysis was conducted using SPM12 and PickAtlas. Connectivity was analyzed for the left and right pulvinar across groups of individuals with PTSD (n = 81), PTSD + DS (n = 49), and controls (n = 51). As compared to PTSD, controls displayed significantly greater pulvinar rsFC with the superior parietal lobule and precuneus. Moreover, as compared to PTSD + DS, controls showed increased pulvinar connectivity with the superior parietal lobule, inferior parietal lobule and the precuneus. PTSD groups did not display stronger connectivity with any region as compared to controls. Last, PTSD had greater rsFC in the supramarginal gyrus relative to PTSD + DS. Reduced connectivity between the pulvinar and PPC may explain impairments to autobiographical memory, self-referential processing, and socioaffective domains in PTSD and PTSD + DS even at "rest." Critically, these alterations appear to be exacerbated in individuals with PTSD + DS, which may have important implications for treatment.
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