Evidence map›Paper›PMID 30091705›Full record

ArticleeLife2018

An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in

David Li-Kroeger, Oguz Kanca, Pei-Tseng Lee, Sierra Cowan, Michael T Lee, Manish Jaiswal, Jose Luis Salazar, Yuchun He, Zhongyuan Zuo, Hugo J Bellen

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

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  11. Constitutive and Conditional Epitope Tagging of Endogenous G-Protein-Coupled Receptors inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  12. Hox gene-specific cellular targeting using split intein Trojan exons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David Li-Kroeger *Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID http://orcid.org/0000-0001-6473-7691
Oguz Kanca *Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Pei-Tseng LeeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID http://orcid.org/0000-0002-7501-7881
Sierra CowanDepartment of Biochemistry and Cell Biology, Rice University Houston, Houston, United States.ORCID http://orcid.org/0000-0003-3530-9326
Michael T LeeDepartment of Biochemistry and Cell Biology, Rice University Houston, Houston, United States.
Manish JaiswalDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Jose Luis SalazarDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Yuchun HeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Zhongyuan ZuoDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Hugo J BellenDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID http://orcid.org/0000-0001-5992-5989

Funding

Transposon induced disruption of most Drosophila genesR01GM067858 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2003 to 2020
$15.7M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8M
PROGRAM IN HUMAN MOLECULAR GENETICST32GM008307 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI SHAULSKY, GAD · 1990 to 2020
$6.6M
Mutidisciplinary Training;Brain Disorders &DevelopmentT32NS043124 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI SWANN, JOHN WILLIAM · 2002 to 2021
$4.6M
Howard Hughes Medical InstituteNICHD NIH HHS U54 HD083092NIGMS NIH HHS R01 GM067858NIGMS NIH HHS T32 GM008307NIH HHS R01GM067858NIH HHS Training grant T32NS043124NINDS NIH HHS T32 NS043124
6 · The paper itself

Abstract

We generated two new genetic tools to efficiently tag genes in

Indexed as

AnimalsClustered Regularly Interspaced Short Palindromic RepeatsDrosophilaEntomologyGenes, ReporterGene TargetingIntegrasesMutagenesis, InsertionalCre recombinaseIntegrasesD. melanogasterDouble Headergene editinggeneticsgenomicsprotein taggingswappable insertion cassetteT2A-GAL4Trojan exons

Identifiers

PMID30091705
PMCPMC6095692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.