Evidence map›Paper›PMID 30091703›Full record

ArticleeLife2018

A discriminator code-based DTD surveillance ensures faithful glycine delivery for protein biosynthesis in bacteria.

Santosh Kumar Kuncha, Katta Suma, Komal Ishwar Pawar, Jotin Gogoi, Satya Brata Routh, Sambhavi Pottabathini, Shobha P Kruparani, Rajan Sankaranarayanan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Mammalian Tolerance to Amino Acid Heterochirality.Chembiochem : a European journal of chemical biology · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Distinct localization of chiral proofreaders resolves organellar translation conflict in plants.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Aminoacyl-tRNA synthetases.RNA (New York, N.Y.) · 2020
    Review
  11. Article
  12. Chiral checkpoints during protein biosynthesis.The Journal of biological chemistry · 2019
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Santosh Kumar Kuncha *CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID http://orcid.org/0000-0002-2538-8342
Katta Suma *CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID http://orcid.org/0000-0003-4667-8768
Komal Ishwar PawarCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID http://orcid.org/0000-0002-1968-9851
Jotin GogoiCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID http://orcid.org/0000-0001-6791-6580
Satya Brata RouthCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Sambhavi PottabathiniCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Shobha P KruparaniCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID http://orcid.org/0000-0002-8955-1647
Rajan SankaranarayananCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID http://orcid.org/0000-0003-4524-9953
Centre for Cellular and Molecular Biology · IN

Funding

Department of Biotechnology , Ministry of Science and Technology Centre of ExcellenceDepartment of Biotechnology , Ministry of Science and Technology DBT-RADepartment of Biotechnology, Ministry of Science and Technology Centre of ExcellenceDepartment of Science and Technology, Ministry of Science and Technology DST-INSPIREScience and Engineering Research Board J. C. Bose Fellowship
6 · The paper itself

Abstract

D-aminoacyl-tRNA deacylase (DTD) acts on achiral glycine, in addition to D-amino acids, attached to tRNA. We have recently shown that this activity enables DTD to clear non-cognate Gly-tRNA

Indexed as

Protein BiosynthesisAminoacyltransferasesAnimalsEscherichia coliGlycineMiceRNA, Transfer, AlaRNA, Transfer, GlyAminoacyltransferasesGlycineRNA, Transfer, AlaRNA, Transfer, Glybiochemistrychemical biologyE. coligenetic codeproofreadingprotein synthesissynthetasetranslationtRNA

Identifiers

PMID30091703
PMCPMC6097841
OpenAlexW2951300939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.