Evidence map›Paper›PMID 30091664›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2018

Acclimatization of low altitude-bred deer mice ( Peromyscus maniculatus) to high altitude.

D Merrill Dane, Khoa Cao, Hua Lu, Cuneyt Yilmaz, Jamie Dolan, Catherine D Thaler, Priya Ravikumar, Kimberly A Hammond, Connie C W Hsia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Evolution and developmental plasticity of lung structure in high-altitude deer mice.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

D Merrill DaneDepartment of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Khoa CaoDepartment of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Hua LuDepartment of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Cuneyt YilmazDepartment of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Jamie DolanDepartment of Evolution, Ecology and Organismal Biology, University of California at Riverside , Riverside, California.
Catherine D ThalerDepartment of Evolution, Ecology and Organismal Biology, University of California at Riverside , Riverside, California.
Priya RavikumarDepartment of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Kimberly A HammondDepartment of Evolution, Ecology and Organismal Biology, University of California at Riverside , Riverside, California.
Connie C W HsiaDepartment of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.ORCID 0000-0003-1995-1407

Funding

Nanoparticle Drug Delivery in Post-Pneumonectomy Compensatory Lung GrowthU01HL111146 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HSIA, CONNIE C. W., NGUYEN, KYTAI TRUONG · 2012 to 2016
$3.2M
Structural Plasticity in Compensatory Lung Growth and RemodelingR01HL134373 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HSIA, CONNIE C. W. · 2017 to 2020
$2.8M
NHLBI NIH HHS R01 HL134373NHLBI NIH HHS U01 HL111146
6 · The paper itself

Abstract

A colony of deer mice subspecies ( Peromyscus maniculatus sonoriensis) native to high altitude (HA) has been maintained at sea level for 18-20 generations and remains genetically unchanged. To determine if these animals retain responsiveness to hypoxia, one group (9-11 wk old) was acclimated to HA (3,800 m) for 8 wk. Age-matched control animals were acclimated to a lower altitude (LA; 252 m). Maximal O

Indexed as

AcclimatizationAltitudeRespirationAnimalsBiometryLungMaleOrgan SizePeromyscusRespiratory Function Testsaerobic capacityhigh altitudehypoxialung diffusing capacitylung morphometryultrastructure

Identifiers

PMID30091664
PMCPMC6295488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.