Evidence map›Paper›PMID 30091401›Full record

ArticleThe Journal of international medical research2018

Cryptogenic and non-cryptogenic liver abscess: A retrospective analysis of 178 cases revealed distinct characteristics.

Jing Chen, Minwei Zhang, Jinlong Chen, Yaogui Ning, Xiaoyang Cai, Li Zhang, Hao Xu, Jing Guo

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Odontogenic liver abscess in one patient.World journal of emergency medicine · 2026
    Article
  3. Article
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  5. GiantBMJ case reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jing ChenDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Minwei ZhangDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Jinlong ChenDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Yaogui NingDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Xiaoyang CaiDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Li ZhangDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Hao XuDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Jing GuoDepartment of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
First Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective To enhance theoretical support of pyogenic liver abscess (PLA) treatment by comparing characteristics of patients with either PLA with an identified infectious origin (non-cryptogenic) or PLA with no obvious underlying cause (cryptogenic). Methods This retrospective study included all first episodes of PLA in adults admitted to a tertiary hospital between 2009 and 2016. Relevant clinical data were collected for patients with cryptogenic or non-cryptogenic PLA and compared across a number of characteristics. Results In all, 178 patients were included: 111 cases (62.4%) of cryptogenic PLA, and 67 cases (37.6%) of non-cryptogenic PLA. Diabetes mellitus was significantly more prevalent in patients with cryptogenic PLA than those with non-cryptogenic PLA. The proportion of multidrug resistance/poly-microbial infection was significantly lower and Klebsiella pneumoniae infection was significantly higher in the cryptogenic versus non-cryptogenic PLA group. Metastatic infection occurred in four patients with cryptogenic PLA only, and all had diabetes and K. pneumoniae infection. Multivariate logistic regression analysis revealed that male sex, diabetes and K. pneumoniae were independent predictors for cryptogenic PLA. Conclusions Cryptogenic and non-cryptogenic PLA have distinctly different characteristics, suggesting a potential need for different treatment approaches.

Indexed as

AdultAgedChinaDiabetes ComplicationsDrug Resistance, Multiple, BacterialFemaleHumansLiver AbscessLiver Abscess, PyogenicMaleMiddle AgedRetrospective Studiesclinical characteristicsCryptogenic pyogenic liver abscessKlebsiella pneumoniaemetastatic infection

Identifiers

PMID30091401
PMCPMC6136014
OpenAlexW2885801824

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.