ArticleTransboundary and emerging diseases2019
Porcine circovirus 3 is highly prevalent in serum and tissues and may persistently infect wild boar (Sus scrofa scrofa).
Article in Transboundary and emerging diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Detection of PCV3 in various sample types from wild boars in Poland.BMC veterinary research · 2026Article
- Evidence of Spillover and Recombination Between Domestic Pigs and Wild Boars Provides New Insights into Porcine Circoviruses.Pathogens (Basel, Switzerland) · 2025Article
- Detection of Porcine Circovirus Type 3 in Free-Ranging Wild Boars and Ticks in Jiangsu Province, China.Viruses · 2025Article
- Surveillance and prevention of infection in clinical xenotransplantation.Clinical microbiology reviews · 2025Review
- Significant Detection of Porcine Circovirus 3 and Porcine Circovirus 4 in Wild Boars from Mid-Western Spain Without Apparent Sanitary Consequences.Animals : an open access journal from MDPI · 2025Article
- Dynamics of PCV2 and PCV3 in the Serum and Oral Fluids of Pigs After PCV2 Vaccination in a Commercial Farm.Vaccines · 2024Article
- Isolation of porcine circovirus 3 using primary porcine bone marrow-derived cells.Virology journal · 2024Article
- Porcine Circovirus Type 3 (PCV3) in Poland: Prevalence in Wild Boar Population in Connection with African Swine Fever (ASF).Viruses · 2024Article
- Epizootiological surveillance of porcine circoviruses in free-ranging wild boars in China.Virologica Sinica · 2023Article
- Revisiting Porcine Circovirus Infection: Recent Insights and Its Significance in the Piggery Sector.Vaccines · 2023Review
- Phylogenetic and Structural Analysis of Porcine Circovirus Type 2 from 2016 to 2021 in Jilin Province, China.Microorganisms · 2023Article
- Porcine circoviruses in wild boars in Nagano Prefecture, Japan.The Journal of veterinary medical science · 2023Article
- Next-Generation Sequencing for Identifying Unknown Pathogens in Sentinel Immunocompromised Hosts.Emerging infectious diseases · 2023Article
- First report on identification and genomic analysis of a novel porcine circovirus (porcine circovirus 4) in cats.Frontiers in microbiology · 2023Article
- Pathogenicity and immune modulation of porcine circovirus 3.Frontiers in veterinary science · 2023Review
- Wilder than intense: higher frequency, variability, and viral flows of porcine circovirus 3 in wild boars and rural farms compared to intensive ones in northern Italy.Frontiers in microbiology · 2023Article
- Genetic Diversity of Porcine Circovirus Types 2 and 3 in Wild Boar in Italy.Animals : an open access journal from MDPI · 2022Article
- Detection and characterisation of porcine circoviruses in wild boars in northeastern Serbia.Veterinarni medicina · 2022Article
- Porcine Circoviruses and Herpesviruses Are Prevalent in an Austrian Game Population.Pathogens (Basel, Switzerland) · 2022Article
- Review
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10 authors.
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Abstract
Porcine circovirus 3 (PCV-3) prevalence has been minimally investigated in wild boar; dynamics of infection and viral tissue distribution are currently unknown. In this study, serum samples from 518 wild boar (from years 2004 to 2018) were used to study frequency of infection. Also, serum samples from 19 boar captured and recaptured at least two times for a period of time from 1 month to 1 year were collected to determine PCV-3 infection dynamics. Finally, to elucidate PCV-3 DNA organic distribution, sera, different tissues and faeces were obtained from 35 additional wild boar. PCV-3 DNA was extracted and amplified with a conventional PCR. For the PCV-3 PCR-positive sera from the longitudinally sampled and different tissue types, a quantitative PCR was performed. Genome sequence was obtained from a number of PCV-3 PCR-positive samples from different years, different time-points of infection and tissues. Obtained results confirmed the susceptibility of wild boar to the virus, showing high frequency of PCV-3 detection (221 out of 518, 42.66%) and demonstrating circulation at least since 2004. Compiled data indicate the possibility of long-term infections, since 5 out of 10 PCV-3 PCR-positive boars longitudinally sampled showed positivity in samplings separated for more than 5 months. All tested tissue types' harboured PCV-3 genome, with the highest percentage of PCR positivity in submandibular lymph node, tonsil, lung, liver, spleen and kidney. The amount of DNA in all tested PCV-3 PCR-positive samples was moderate to low. All partial and complete PCV-3 sequences obtained from wild boar displayed high nucleotide identity, higher than 98%. In conclusion, this study further confirms that wild boar is susceptible to PCV-3 infection, showing high frequency of detection in this animal species. Furthermore, PCV-3 can be found in different tissues of wild boar and is apparently able to cause persistent infection.
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