Evidence map›Paper›PMID 30091065›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2018

Decreasing trend of bone mineral density in US multiethnic population: analysis of continuous NHANES 2005-2014.

Y Xu, Q Wu

Abstract read
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The Effects ofNutrients · 2023
    Pooled it
  2. Pooled it
  3. Trial
  4. Cremation weights for an Italian contemporary sample.Journal of forensic sciences · 2026
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  12. Racial and Ethnic Disparities in Bone Health and Outcomes in the United States.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
    Review
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  16. Cortical threaded pedicle screw improves fatigue strength in decreased bone quality.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Y XuNevada Institute of Personalized Medicine, University of Nevada, Las Vegas, 4505 Maryland Parkway, Las Vegas, NV, 89154-4009, USA.
Q WuNevada Institute of Personalized Medicine, University of Nevada, Las Vegas, 4505 Maryland Parkway, Las Vegas, NV, 89154-4009, USA. qing.wu@unlv.edu.ORCID http://orcid.org/0000-0003-4679-8903

Funding

Developing Model-based Bone Density Reference Values for African-American WomenR15MD010475 · NIMHD · UNIVERSITY OF NEVADA LAS VEGAS · PI WU, QING · 2017 to 2017
$448k
National Institute on Minority Health and Health Disparities R15MD010475NIMHD NIH HHS R15 MD010475University of Nevada, Las Vegas 917D-Wu-KF
6 · The paper itself

Abstract

Studies examining recent bone mineral density (BMD) trends in the US population are limited. In our study, we found that age-adjusted mean BMD among US men and women was stable from 2005 to 2010, but then declined in 2013-2014. We also explored factors associated with decreasing BMD in recent years.

introductionOsteoporosis prevalence in the USA declined between 1988 and 2006, while the declining trend in hip fracture may have plateaued in 2013-2014. We aimed to examine whether there has been a corresponding change in BMD trajectory for the US population.

methodsContinuous National Health and Nutrition Examination Survey (NHANES) data from 2005-2006 to 2013-2014 were analyzed to examine BMD trends among US men and women aged 30 years and older and among different race/ethnicity subgroups. ANOVA and Bonferroni adjustments were used to examine the differences in mean BMD, and multiple linear regressions adjusting for potential confounding effects were employed to examine BMD trends.

resultsAfter age standardization, the mean BMD of the femur neck for the first three NHANES cycles was stable (all p > 0.1) in both men and women, but significantly decreased in 2013-2014, from 0.864 g/cm

conclusionsAge-adjusted mean BMD decreased in 2013-2014 in both men and women, and this significant decrease was also observed in sensitivity and subgroup analyses. The decreased BMD in 2013-2014 still remained significant even after being adjusted for multiple potentially confounding effects.

Indexed as

Absorptiometry, PhotonAdultAgedAgingBlack or African AmericanBone DensityFemaleFemur NeckForecastingHispanic or LatinoHumansLinear ModelsMaleMiddle AgedNutrition SurveysOsteoporosisAgingBone mineral densityDXANHANESTrend

Identifiers

PMID30091065
PMCPMC6192842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.