Evidence map›Paper›PMID 30090998›Full record

ReviewInsights into imaging2018

Facet joint syndrome: from diagnosis to interventional management.

Romain Perolat, Adrian Kastler, Benjamin Nicot, Jean-Michel Pellat, Florence Tahon, Arnaud Attye, Olivier Heck, Kamel Boubagra, Sylvie Grand, Alexandre Krainik

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Insights into imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 104 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 4 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04542798 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Central Sensitization and Aberrant Nerve Sprouting Possible Explanations for RFA Failure of MBDR in CLBP of FJ Origin: CRF Versus WCRF or PRF-DRG Randomized Clinical Trial

TypeinterventionalSponsorHospital General Universitario de ValenciaRan2020 to 2024Enrolled80ConditionsLow Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central SensitisationArmsRadiofrequency COSMAN
NCT06804551 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

A Single-center, Prospective, Double-blind, Randomized Controlled Trial Evaluating Iovera° Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Facet-mediated Chronic Low Back Pain

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2025 to 2027Enrolled30ConditionsChronic Low-back PainArmsiovera system, Radiofrequency ablation alone
NCT07214844 narecruitingnot on this mapstarted 2026, after this paper: background citation

A Prospective, Randomized, Assessor Blind, Active-controlled, Single-center Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Facet-mediated Chronic Low Back Pain

TypeinterventionalSponsorMontefiore Medical CenterRan2026 to 2028Enrolled110ConditionsLow Back Pain, ChronicArmsIovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA)
3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 4 syntheses or guidelines pooled it, 265 citations in OpenAlex.

  1. Effectiveness of single-photon emission computed tomography (SPECT/SPECT-CT) in predicting therapeutic response to facet interventions for facet joint-related low back pain: A systematic review and Meta-Analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
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  4. Percutaneous radiofrequency ablation and endoscopic neurotomy for lumbar facet joint syndrome: are they good enough?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Pooled it
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  7. Efficacy and safety of [European journal of nuclear medicine and molecular imaging · 2026
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  13. ISSLS Prize in Bioengineering Science 2026: Hidden in Plain Sight: Machine Learning-Assisted MRI Reveals Novel Vertebral Body Biomarkers of Chronic Low Back Pain in Humans.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Romain PerolatClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France. rperolat@chu-grenoble.fr.
Adrian KastlerClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France.
Benjamin NicotService de Neurochirurgie, Centre Hospitalier Universitaire A. Michallon, Grenoble, France.
Jean-Michel PellatCentre d'évaluation et du traitement de la douleur, Groupe hospitalier mutualiste, Grenoble, France.
Florence TahonClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France.
Arnaud AttyeClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France.
Olivier HeckClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France.
Kamel BoubagraClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France.
Sylvie GrandClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France.
Alexandre KrainikClinique Universitaire de Neuroradiologie, Centre Hospitalier Universitaire A Michallon, Grenoble, France.
Centre Hospitalier Universitaire de Grenoble · FRGroupe Hospitalier Mutualiste de Grenoble · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low back pain (LBP) is the most common pain syndrome, and is an enormous burden and cost generator for society. Lumbar facet joints (FJ) constitute a common source of pain, accounting for 15-45% of LBP. Facet joint degenerative osteoarthritis is the most frequent form of facet joint pain. History and physical examination may suggest but not confirm facet joint syndrome. Although imaging (radiographs, MRI, CT, SPECT) for back pain syndrome is very commonly performed, there are no effective correlations between clinical symptoms and degenerative spinal changes. Diagnostic positive facet joint block can indicate facet joints as the source of chronic spinal pain. These patients may benefit from specific interventions to eliminate facet joint pain such as neurolysis, by radiofrequency or cryoablation. The purpose of this review is to describe the anatomy, epidemiology, clinical presentation, and radiologic findings of facet joint syndrome. Specific interventional facet joint management will also be described in detail. TEACHING POINTS: • Lumbar facet joints constitute a common source of pain accounting of 15-45%. • Facet arthrosis is the most frequent form of facet pathology. • There are no effective correlations between clinical symptoms, physical examination and degenerative spinal changes. • Diagnostic positive facet joint block can indicate facet joints as the source of pain. • After selection processing, patients may benefit from facet joint neurolysis, notably by radiofrequency or cryoablation.

Indexed as

BlockCryoablationFacet jointLow back painNeurolysisRadiofrequency

Identifiers

PMID30090998
PMCPMC6206372
OpenAlexW2887691942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.