Evidence map›Paper›PMID 30090966›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Disease-related patterns of in vivo pathology in Corticobasal syndrome.

Flavia Niccolini, Heather Wilson, Stephanie Hirschbichler, Tayyabah Yousaf, Gennaro Pagano, Alexander Whittington, Silvia P Caminiti, Roberto Erro, Janice L Holton, Zane Jaunmuktane and 9 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Cognitive impairment in Parkinson's disease and other parkinsonian syndromes.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  2. Relationships between hypometabolism and both β-amyloid and tau PET in corticobasal syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Imaging pathological tau in atypical parkinsonisms: A review.Clinical parkinsonism & related disorders · 2022
    Review
  8. Article
  9. Article
  10. IntegratedFrontiers in aging neuroscience · 2021
    Article
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 3 countries.

Flavia NiccoliniNeurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.
Heather WilsonNeurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.
Stephanie HirschbichlerSobell Department of Motor Neuroscience, UCL Institute of Neurology, London, UK.
Tayyabah YousafNeurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.
Gennaro PaganoNeurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.
Alexander WhittingtonDivision of Brain Sciences, Department of Medicine, Imperial College London, London, UK.
Silvia P CaminitiNeurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.
Roberto ErroCenter for Neurodegenerative Diseases (CEMAND) Department of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Janice L HoltonDivision of Neuropathology, UCL Institute of Neurology, London, UK.
Zane JaunmuktaneDivision of Neuropathology, UCL Institute of Neurology, London, UK.
Marcello EspositoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy.
Davide MartinoDepartment of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Ali AbdulImanova Ltd, Centre for Imaging Sciences, Hammersmith Hospital, London, UK.
Jan PasschierImanova Ltd, Centre for Imaging Sciences, Hammersmith Hospital, London, UK.
Eugenii A RabinerImanova Ltd, Centre for Imaging Sciences, Hammersmith Hospital, London, UK.
Roger N GunnDivision of Brain Sciences, Department of Medicine, Imperial College London, London, UK.
Kailash P BhatiaSobell Department of Motor Neuroscience, UCL Institute of Neurology, London, UK.
Marios PolitisNeurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK. marios.politis@kcl.ac.uk.
Alzheimer’s Disease Neuroimaging Initiative
King's College London · GBHammersmith Hospital · GBUniversity College London · GBUniversity of Calgary · CAUniversity of Salerno · ITSobell House · GBWellcome Centre for Human Neuroimaging · GB

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

purposeTo assess disease-related patterns of in vivo pathology in 11 patients with Corticobasal Syndrome (CBS) compared to 20 healthy controls and 33 mild cognitive impairment (MCI) patients due to Alzheimer's disease.

methodsWe assessed tau aggregates with [

resultsCBS patients showed increases in [

conclusionsOur findings demonstrate disease-related patterns of in vivo tau and microstructural pathology in the absence of amyloid-β, which distinguish CBS from non-affected individuals and MCI patients.

Indexed as

AgedBiological TransportCarbolinesCase-Control StudiesCognitive DysfunctionFemaleHumansKineticsMagnetic Resonance ImagingMaleMiddle AgedNeurodegenerative DiseasesPositron-Emission TomographyWhite Matter7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolinesCorticobasal syndromeMRIPETTau

Identifiers

PMID30090966
PMCPMC6208819
OpenAlexW2887607716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.