Evidence map›Paper›PMID 30090696›Full record

ArticleNeuroImage. Clinical2018

Brain tissue pulsatility is related to clinical features of Parkinson's disease.

Zahra Shirzadi, Andrew D Robertson, Arron W Metcalfe, Sarah Duff-Canning, Connie Marras, Anthony E Lang, Mario Masellis, Bradley J MacIntosh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Characterizing pulsatility in distal cerebral arteries using 4D flow MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zahra ShirzadiDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada. Electronic address: zahra.shirzadi@mail.utoronto.ca.
Andrew D RobertsonHurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Arron W MetcalfeHurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Sarah Duff-CanningMorton and Gloria Shulman Movement Disorders Centre and the Edmond J Safra Program in Parkinson's disease, Toronto western Hospital, University of Toronto, Toronto, Ontario, Canada.
Connie MarrasMorton and Gloria Shulman Movement Disorders Centre and the Edmond J Safra Program in Parkinson's disease, Toronto western Hospital, University of Toronto, Toronto, Ontario, Canada.
Anthony E LangMorton and Gloria Shulman Movement Disorders Centre and the Edmond J Safra Program in Parkinson's disease, Toronto western Hospital, University of Toronto, Toronto, Ontario, Canada.
Mario MasellisHurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada; Division of Neurology, University of Toronto, Toronto, Ontario, Canada.
Bradley J MacIntoshDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
University of Toronto · CASunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study investigated whether brain tissue pulsatility is associated with features of disease severity in Parkinson's disease (PD). Methods: Data were extracted from the Parkinson's Progression Markers Initiative among 81 adults with PD (confirmed with DATSCAN™). Brain tissue pulsatility was computed using resting state blood oxygenation level dependent (BOLD) MRI in white matter (WM), referred to as BOLD Results: Motor impairment ( Conclusion: Our findings show that brain tissue pulsatility from BOLD images in WM is related to neurological and vascular features in PD. BOLD

Indexed as

AdultAgedBrainFemaleHumansMaleMiddle AgedOxygen ConsumptionParkinson DiseasePsychomotor PerformancePulsatile FlowBlood oxygenation level dependent MRIBrain tissue pulsatilityParkinson's diseaseVascular risk factorsWhite matter

Identifiers

PMID30090696
PMCPMC6079564
OpenAlexW2884034859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.