Evidence map›Paper›PMID 30090561›Full record

ArticleToxicology research2018

Involvement of histone hypoacetylation in INH-induced rat liver injury.

Ling-Yan Zhu, Qi Ren, Yu-Hong Li, Yi-Yang Zhang, Jin-Feng Li, Ying-Shu Li, Zhe Shi, Fu-Min Feng

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Ling-Yan ZhuHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.
Qi RenHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.
Yu-Hong LiHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.
Yi-Yang ZhangHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.
Jin-Feng LiHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.
Ying-Shu LiHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.
Zhe ShiHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.
Fu-Min FengHebei Province Key Laboratory of Occupational Health and Safety for Coal Industry , School of Public Health , North China University of Science and Technology , Tangshan 063210 , China . Email: fm_feng@sina.com ; ; Tel: +86 8805562.ORCID 0000-0001-6506-2235
North China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores the mechanism of histone acetylation under the effect of oxidative stress in rat liver injury induced by isoniazid (INH). Fifty-six adult SD rats were selected and divided randomly into INH groups (48) and control (8). Rats in INH groups were intragastrically injected with 55 mg kg

Identifiers

PMID30090561
PMCPMC6062348
OpenAlexW2763512930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.