Evidence map›Paper›PMID 30090517›Full record

ArticleToxicology research2017

Biosafety study and mechanism comparison on two types of silica with different nanostructures.

Yang Zhang, Xianhui Chen, Bo Zhao, Hounan Wu, Lan Yuan, Hua Zhang, Wenbing Dai, Bing He, Gengmei Xing, Qiang Zhang and 1 more

Abstract read
In one paragraph

Article in Toxicology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yang ZhangBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.
Xianhui ChenBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.
Bo ZhaoBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.
Hounan WuMedical and Healthy Analytical Center , Peking University , Beijing 100191 , China.
Lan YuanMedical and Healthy Analytical Center , Peking University , Beijing 100191 , China.
Hua ZhangBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.
Wenbing DaiBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.
Bing HeBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.
Gengmei XingCAS Key Laboratory for Biomedical Effects of Nanomaterial & Nanosafety , Institute of High Energy Physics , Chinese Academy of Science (CAS) , Beijing 100049 , China.
Qiang ZhangBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.
Xueqing WangBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: wangxq@bjmu.edu.cn ; Tel: +86-10-82805935.ORCID 0000-0003-4732-630X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silica is frequently used in oral drug delivery; however, its biosafety, particularly concerned with its nanostructure, has not been comprehensively studied yet. Here, the

Identifiers

PMID30090517
PMCPMC6062300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.