Evidence map›Paper›PMID 30090505›Full record

ArticleToxicology research2017

LncRNA-MALAT1 as a novel biomarker of cadmium toxicity regulates cell proliferation and apoptosis.

Qinhai Huang, Qian Lu, Baoxin Chen, Huanyu Shen, Qun Liu, Zhiheng Zhou, Yixiong Lei

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Qinhai HuangSchool of Public Health , Guangzhou Medical University , Guangzhou 510182 , People's Republic of China . Email: gz-leizeng@163.com.ORCID 0000-0002-0141-3478
Qian LuShenzhen Longgang District Center for Disease Control and Prevention , Shenzhen 518172 , P.R. China.
Baoxin ChenSchool of Public Health , Guangzhou Medical University , Guangzhou 510182 , People's Republic of China . Email: gz-leizeng@163.com.
Huanyu ShenSchool of Public Health , Guangzhou Medical University , Guangzhou 510182 , People's Republic of China . Email: gz-leizeng@163.com.
Qun LiuSchool of Public Health , Guangzhou Medical University , Guangzhou 510182 , People's Republic of China . Email: gz-leizeng@163.com.
Zhiheng ZhouMassachusetts General Hospital , Harvard Medical School , Boston , Massachusetts 02114 , USA.
Yixiong LeiSchool of Public Health , Guangzhou Medical University , Guangzhou 510182 , People's Republic of China . Email: gz-leizeng@163.com.
State Council of the People's Republic of China · CNCenters for Disease Control and Prevention · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) and its compounds are well-known human carcinogens, but the mechanisms underlying the carcinogenesis are not well understood. This study aimed to investigate whether lncRNA-MALAT1 could serve as a novel biomarker of Cd toxicity in cells, animals and Cd-exposed workers, and regulate cell proliferation, apoptosis, migration and invasion. MALAT1 expression increased gradually in CdCl

Identifiers

PMID30090505
PMCPMC6062301
OpenAlexW2595364313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.