Evidence map›Paper›PMID 30090496›Full record

ArticleToxicology research2017

Development of a BALB/c mouse model for food allergy: comparison of allergy-related responses to peanut agglutinin, β-lactoglobulin and potato acid phosphatase.

Chen Chen, Lu Lianhua, Sun Nana, Li Yongning, Jia Xudong

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Frontiers in cellular and infection microbiology · 2022
    Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Chen ChenKey Laboratory of Trace Element Nutrition MOH , National Institute for Nutrition and Health , Chinese Center for Disease Control and Prevention , Beijing 100050 , PR China.ORCID 0000-0002-9840-3945
Lu LianhuaShandong Center for Disease Control and Prevention , Jinan 250014 , Shandong , China.
Sun NanaKey Laboratory of Food Safety Risk Assessment of Ministry of Health , China National Center for Food Safety Risk Assessment , Beijing 100021 , PR China . Email: jiaxudong@cfsa.net.cn ; ; Tel: +86 10 67770977.
Li YongningKey Laboratory of Food Safety Risk Assessment of Ministry of Health , China National Center for Food Safety Risk Assessment , Beijing 100021 , PR China . Email: jiaxudong@cfsa.net.cn ; ; Tel: +86 10 67770977.
Jia XudongKey Laboratory of Food Safety Risk Assessment of Ministry of Health , China National Center for Food Safety Risk Assessment , Beijing 100021 , PR China . Email: jiaxudong@cfsa.net.cn ; ; Tel: +86 10 67770977.
In-Q-Tel · USChinese Center For Disease Control and Prevention · CNShandong Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to develop a BALB/c mouse model for comprehensively assessing food allergies. Serum specific IgE and IgG1 antibodies against protein (PNA, β-LG, and PAP) were induced in intraperitoneally sensitized BALB/c mice. On day 28, blood was collected to obtain the serum, and the splenocytes were cultured. On day 30, mice were challenged with antigen by intraperitoneal injection or intragastric administration, and the physiological and immunological responses to the antigen were studied. A general finding was that allergenicity-related parameters in the mice treated with PNA were statistically higher than those in the mice treated with PAP (

Identifiers

PMID30090496
PMCPMC6061913
OpenAlexW2575221199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.