Evidence map›Paper›PMID 30090475›Full record

ArticleToxicology research2017

Lipid droplets alleviate cadmium induced cytotoxicity in

Selvaraj Rajakumar, Vasanthi Nachiappan

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Selvaraj RajakumarBiomembrane Lab , Department of Biochemistry , Centre of Excellence in Life Sciences , Bharathidasan University , Tiruchirappalli 620024 , Tamil Nadu , India . Email: vasanthibch@gmail.com ; ; Tel: +91 431 2904866.ORCID 0000-0001-9891-3657
Vasanthi NachiappanBiomembrane Lab , Department of Biochemistry , Centre of Excellence in Life Sciences , Bharathidasan University , Tiruchirappalli 620024 , Tamil Nadu , India . Email: vasanthibch@gmail.com ; ; Tel: +91 431 2904866.
National Institute of Technology Tiruchirappalli · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) induces oxidative stress that generates reactive oxygen species (ROS) and increased lipid accumulation. However, very little is known about the role of oxidative stress in triacylglycerol (TAG) accumulation. TAG accumulation is deleterious to health and may result in obesity-associated metabolic syndrome. Hence TAG accumulation plays an important role in Cd induced cytotoxicity. The exposure of Wild-type (WT) cells to Cd, resulted in TAG accumulation and also enhanced viability when compared to TAG mutants (

Identifiers

PMID30090475
PMCPMC6062051
OpenAlexW2528205577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.