Evidence map›Paper›PMID 30090401›Full record

ArticleToxicology research2016

Bone morphogenetic protein-7 prevented epithelial-mesenchymal transition in RLE-6TN cells.

Yan Wang, Di Liang, Zhonghui Zhu, Xiaoli Li, Guoliang An, Piye Niu, Li Chen, Lin Tian

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. The role of inflammation in silicosis.Frontiers in pharmacology · 2024
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yan WangSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Di LiangSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Zhonghui ZhuSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Xiaoli LiSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Guoliang AnSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Piye NiuSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Li ChenSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Lin TianSchool of Public Health , Capital Medical University , Beijing 100069 , China . Email: tian_lin@163.com ; ; Tel: +86 10 83911506.
Beijing Administration Institute · CNCapital Medical University · CNCapital University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone morphogenetic protein-7 (BMP-7) plays an important role in the epithelial-mesenchymal transition (EMT) process, and has been identified as the most potent factor that can promote mesenchymal-epithelial transition (MET) and reduce organ fibrosis. Here we examined the important role of BMP-7 in silica-induced EMT and investigated the relationship between BMP-7 and the balance of EMT/MET. We found that silica induced EMT and decreased the expression of BMP-7

Identifiers

PMID30090401
PMCPMC6062346
OpenAlexW2301933375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.