Evidence map›Paper›PMID 30090378›Full record

ArticleToxicology research2016

Differential expression of serum proteins in rats subchronically exposed to arsenic identified by iTRAQ-based proteomic technology-14-3-3 ζ protein to serve as a potential biomarker.

Jin Hui Zhang, Ying Li, Xuan Bo Song, Xiao Hong Ji, Hong Na Sun, Hui Wang, Song Bin Fu, Li Jun Zhao, Dian Jun Sun

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Arsenic disrupts extracellular vesicle-mediated signaling in regenerating myofibers.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  2. Serum Proteomic Profiling Analysis of Rats Chronically Exposed to Arsenic.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Jin Hui ZhangKey Lab of Etiologic Epidemiology of National Health and Family Planning Commission , Key Lab of Etiologic Epidemiology of Education Bureau of Heilongjiang Province , The Center for Endemic Disease Control , Chinese Center for Disease Control and Prevention , Harbin Medical University , Harbin 150081 , China . Email: zhaolijun1012@163.com ; Email: hrbmusdj@163.com ; ; Tel: (+86)-451-8750- 2980.
Ying LiKey Lab of Etiologic Epidemiology of National Health and Family Planning Commission , Key Lab of Etiologic Epidemiology of Education Bureau of Heilongjiang Province , The Center for Endemic Disease Control , Chinese Center for Disease Control and Prevention , Harbin Medical University , Harbin 150081 , China . Email: zhaolijun1012@163.com ; Email: hrbmusdj@163.com ; ; Tel: (+86)-451-8750- 2980.
Xuan Bo SongKey Lab of Etiologic Epidemiology of National Health and Family Planning Commission , Key Lab of Etiologic Epidemiology of Education Bureau of Heilongjiang Province , The Center for Endemic Disease Control , Chinese Center for Disease Control and Prevention , Harbin Medical University , Harbin 150081 , China . Email: zhaolijun1012@163.com ; Email: hrbmusdj@163.com ; ; Tel: (+86)-451-8750- 2980.
Xiao Hong JiKey Lab of Etiologic Epidemiology of National Health and Family Planning Commission , Key Lab of Etiologic Epidemiology of Education Bureau of Heilongjiang Province , The Center for Endemic Disease Control , Chinese Center for Disease Control and Prevention , Harbin Medical University , Harbin 150081 , China . Email: zhaolijun1012@163.com ; Email: hrbmusdj@163.com ; ; Tel: (+86)-451-8750- 2980.
Hong Na SunKey Lab of Etiologic Epidemiology of National Health and Family Planning Commission , Key Lab of Etiologic Epidemiology of Education Bureau of Heilongjiang Province , The Center for Endemic Disease Control , Chinese Center for Disease Control and Prevention , Harbin Medical University , Harbin 150081 , China . Email: zhaolijun1012@163.com ; Email: hrbmusdj@163.com ; ; Tel: (+86)-451-8750- 2980.
Hui WangCommunity Health Service Center of Nanxiang Town , Jiading District , Shanghai 201802 , China.
Song Bin FuThe Laboratory of Medical Genetics , Harbin Medical University , Harbin 150081 , China.
Li Jun ZhaoKey Lab of Etiologic Epidemiology of National Health and Family Planning Commission , Key Lab of Etiologic Epidemiology of Education Bureau of Heilongjiang Province , The Center for Endemic Disease Control , Chinese Center for Disease Control and Prevention , Harbin Medical University , Harbin 150081 , China . Email: zhaolijun1012@163.com ; Email: hrbmusdj@163.com ; ; Tel: (+86)-451-8750- 2980.
Dian Jun SunKey Lab of Etiologic Epidemiology of National Health and Family Planning Commission , Key Lab of Etiologic Epidemiology of Education Bureau of Heilongjiang Province , The Center for Endemic Disease Control , Chinese Center for Disease Control and Prevention , Harbin Medical University , Harbin 150081 , China . Email: zhaolijun1012@163.com ; Email: hrbmusdj@163.com ; ; Tel: (+86)-451-8750- 2980.
Center for Disease Control · TWHarbin Medical University · CNIn-Q-Tel · USCommunity Health Center · USInstitute of Endemic Disease Control in Shandong Province · CNLaboratoire de Génétique Médicale

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arsenic is a multi-system toxicant. However, the mechanism of arsenic toxicity is not fully clarified and few effective protein biomarkers could be used for arsenic poisoning. This study was to investigate the differentially expressed proteins in the serum of rats subchronically exposed to arsenic. Sixty male rats were randomly divided into four groups, and the dose of sodium arsenite in drinking water for each group was 0, 2, 10, and 50 mg L

Identifiers

PMID30090378
PMCPMC6062359
OpenAlexW2263470545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.