Evidence map›Paper›PMID 30090345›Full record

ArticleToxicology research2016

A quantitative proteomic approach for unveiling novel mechanisms associated with MeHg-induced toxicity: effects on the methylation cycle.

Pablo Cabezas-Sanchez, Estefania Garcia-Calvo, Carmen Camara, Jose L Luque-Garcia

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pablo Cabezas-SanchezDepartment of Analytical Chemistry , Faculty of Chemistry , Complutense University of Madrid , 28040 , Madrid , Spain . Email: lluque@quim.ucm.es ; Tel: +34913944318.
Estefania Garcia-CalvoDepartment of Analytical Chemistry , Faculty of Chemistry , Complutense University of Madrid , 28040 , Madrid , Spain . Email: lluque@quim.ucm.es ; Tel: +34913944318.
Carmen CamaraDepartment of Analytical Chemistry , Faculty of Chemistry , Complutense University of Madrid , 28040 , Madrid , Spain . Email: lluque@quim.ucm.es ; Tel: +34913944318.
Jose L Luque-GarciaDepartment of Analytical Chemistry , Faculty of Chemistry , Complutense University of Madrid , 28040 , Madrid , Spain . Email: lluque@quim.ucm.es ; Tel: +34913944318.
Universidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylmercury (MeHg) is still a major threat for human health and the environment due to its extremely high toxicity that mainly affects the nervous system. Despite the great efforts made during the last few decades, the specific molecular mechanisms involved in MeHg-induced toxicity are still not completely unveiled. In this work we explored such mechanisms using neuroblastoma cells (Neuro-2a) and SILAC as a quantitative proteomic approach. We found that exposure of Neuro-2a cells to 2 mg L

Identifiers

PMID30090345
PMCPMC6062361
OpenAlexW2175269760

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.