Evidence map›Paper›PMID 30090342›Full record

ArticleToxicology research2016

Screening and validation for plasma biomarkers of nephrotoxicity based on metabolomics in male rats.

Yubo Li, Haoyue Deng, Liang Ju, Xiuxiu Zhang, Zhenzhu Zhang, Zhen Yang, Lei Wang, Zhiguo Hou, Yanjun Zhang

Abstract read
In one paragraph

Article in Toxicology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yubo LiTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Haoyue DengTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Liang JuTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Xiuxiu ZhangTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Zhenzhu ZhangTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Zhen YangTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Lei WangTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Zhiguo HouTianjin State Key Laboratory of Modern Chinese Medicine , School of Traditional Chinese Materia Medica , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China.
Yanjun ZhangTianjin State Key Laboratory of Modern Chinese Medicine , Tianjin University of Traditional Chinese Medicine , 312 Anshan west Road , Tianjin 300193 , China . Email: tianjin_tcm001@sina.com ; ; Tel: +86-22-59596221.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, drug-induced nephrotoxicity is widespread and seriously affects human health. However, the conventional indexes of renal function lack sensitivity, leading to a delay in the detection of nephrotoxicity. Therefore, we need to identify more sensitive indexes for evaluating nephrotoxicity. In this study, we used gentamicin (100 mg kg

Identifiers

PMID30090342
PMCPMC6062367

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.