Evidence map›Paper›PMID 30089922›Full record

ArticleNature2018

Large deletions induced by Cas9 cleavage.

Fatwa Adikusuma, Sandra Piltz, Mark A Corbett, Michelle Turvey, Shaun R McColl, Karla J Helbig, Michael R Beard, James Hughes, Richard T Pomerantz, Paul Q Thomas

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 238 papers.

0numbers the graph read from it
0cells of the map it votes in
238citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

238 citing papers in PubMed.

  1. Article
  2. Article
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  8. A primer on prime: A prime editing update from advances to first-in-human trial.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Strategies to eliminate native T cell receptors for adoptive T cell therapies.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Review
  13. Review
  14. Haplotype editing with CRISPR-Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  15. Review
  16. Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  17. Article
  18. Review
  19. Article
  20. Article

178 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Fatwa AdikusumaSchool of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
Sandra PiltzSchool of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
Mark A CorbettRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.
Michelle TurveySingapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Shaun R McCollSchool of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
Karla J HelbigSchool of Life Sciences, La Trobe University, Melbourne, Victoria, Australia.
Michael R BeardSchool of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
James HughesSchool of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
Richard T PomerantzFels Institute for Cancer Research, Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.
Paul Q ThomasSchool of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia. paul.thomas@adelaide.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.