Evidence map›Paper›PMID 30089917›Full record

ArticleNature2018

Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.

Eva Kummer, Marc Leibundgut, Oliver Rackham, Richard G Lee, Daniel Boehringer, Aleksandra Filipovska, Nenad Ban

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 136 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Transplantation ofMicrobiology (Reading, England) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. A roadmap for ribosome assembly in human mitochondria.Nature structural & molecular biology · 2024
    Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Eva KummerDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich, Switzerland.
Marc LeibundgutDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich, Switzerland.
Oliver RackhamHarry Perkins Institute of Medical Research, Centre for Medical Research, QEII Medical Centre and School of Molecular Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
Richard G LeeHarry Perkins Institute of Medical Research, Centre for Medical Research, QEII Medical Centre and School of Molecular Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
Daniel BoehringerDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich, Switzerland.
Aleksandra FilipovskaHarry Perkins Institute of Medical Research, Centre for Medical Research, QEII Medical Centre and School of Molecular Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
Nenad BanDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich, Switzerland. ban@mol.biol.ethz.ch.
ETH Zurich · CHHarry Perkins Institute of Medical Research · AUQueen Elizabeth II Medical Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria maintain their own specialized protein synthesis machinery, which in mammals is used exclusively for the synthesis of the membrane proteins responsible for oxidative phosphorylation

Indexed as

Cryoelectron MicroscopyMammalsPeptide Chain Initiation, TranslationalAnimalsCodon, InitiatorEukaryotic Initiation FactorsMitochondriaMitochondrial ProteinsModels, MolecularRNA, MitochondrialRNA, Transfer, MetCodon, InitiatorEukaryotic Initiation FactorsfMet-tRNA(fMet)Mitochondrial ProteinsRNA, MitochondrialRNA, Transfer, Met

Identifiers

PMID30089917
OpenAlexW2886477036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.