Evidence map›Paper›PMID 30089902›Full record

ArticleNature2018

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Marcus Fulde, Felix Sommer, Benoit Chassaing, Kira van Vorst, Aline Dupont, Michael Hensel, Marijana Basic, Robert Klopfleisch, Philip Rosenstiel, André Bleich and 3 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 107 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 1 synthesis or guideline pooled it, 196 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Advances in Fecal Microbiota Transplantation for Gut Dysbiosis-Related Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  19. Article
  20. Review

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 3 countries.

Marcus FuldeInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
Felix SommerDepartment of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.
Benoit ChassaingNeuroscience Institute, Georgia State University, Atlanta, GA, USA.
Kira van VorstInstitute of Microbiology and Epizootics, Department of Veterinary Medicine at the Freie Universität Berlin, Berlin, Germany.
Aline DupontInstitute for Medical Microbiology, RWTH University Hospital Aachen, Aachen, Germany.
Michael HenselDivision of Microbiology, University of Osnabrück, Osnabrück, Germany.
Marijana BasicInstitute for Laboratory Animal Science, Hannover Medical School, Hannover, Germany.
Robert KlopfleischInstitute of Veterinary Pathology, Department of Veterinary Medicine at the Freie Universität Berlin, Berlin, Germany.
Philip RosenstielInstitute of Clinical Molecular Biology (IKMB), Kiel University, Kiel, Germany.
André BleichInstitute for Laboratory Animal Science, Hannover Medical School, Hannover, Germany.
Fredrik BäckhedDepartment of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.
Andrew T GewirtzInstitute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
Mathias W HornefInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany. mhornef@ukaachen.de.
Medizinische Hochschule Hannover · DEFreie Universität Berlin · DEGeorgia State University · USKiel University · DEOsnabrück University · DERWTH Aachen University · DESahlgrenska University Hospital · SEUniversitätsklinikum Aachen · DEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in enteric microbiota are associated with several highly prevalent immune-mediated and metabolic diseases

Indexed as

AgingAnimalsAnimals, NewbornCrosses, GeneticEnvironmentFemaleFlagellinGastrointestinal MicrobiomeHomeostasisHost Microbial InteractionsHousing, AnimalIntestinal MucosaMaleMiceMice, Inbred C57BLPregnancyFlagellinToll-Like Receptor 5

Identifiers

PMID30089902
OpenAlexW2886322630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.