Evidence map›Paper›PMID 30089820›Full record

ArticleEuropean journal of human genetics : EJHG2018

A patient-specific induced pluripotent stem cell model for West syndrome caused by ST3GAL3 deficiency.

Laura van Diepen, Falk F R Buettner, Dirk Hoffmann, Christina T Thiesler, Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbach, Lars R Jensen, Doris Steinemann, Simon Edvardson, Orly Elpeleg and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of human genetics : EJHG, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Laura van DiepenInterfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Falk F R BuettnerInstitute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany.ORCID http://orcid.org/0000-0002-8468-1223
Dirk HoffmannREBIRTH-Cluster of Excellence, Hannover Medical School, Hannover, Germany.
Christina T ThieslerInstitute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany.
Oliver von Bohlen Und HalbachInstitute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-2613-2517
Viola von Bohlen Und HalbachInstitute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Lars R JensenInterfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-9608-8224
Doris SteinemannREBIRTH-Cluster of Excellence, Hannover Medical School, Hannover, Germany.
Simon EdvardsonMonique and Jacques Roboh Department of Genetic Research, Hadassah, Hebrew University Medical Center, Jerusalem, Israel.
Orly ElpelegMonique and Jacques Roboh Department of Genetic Research, Hadassah, Hebrew University Medical Center, Jerusalem, Israel.
Axel SchambachREBIRTH-Cluster of Excellence, Hannover Medical School, Hannover, Germany.
Rita Gerardy-SchahnInstitute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany.
Andreas W KussInterfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany. kussa@uni-greifswald.de.ORCID http://orcid.org/0000-0002-9401-4627
Medizinische Hochschule Hannover · DEUniversitätsmedizin Greifswald · DEHadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ST3GAL3 encodes the Golgi enzyme beta-galactoside-alpha-2,3-sialyltransferase-III that in humans forms, among others, the sialyl Lewis a (sLe

Indexed as

Animalsbeta-Galactoside alpha-2,3-SialyltransferaseCells, CulturedCerebral CortexFemaleFibroblastsHumansInduced Pluripotent Stem CellsInfantLectinsMiceMutationNeuronsPrecision MedicinePrimary Cell CultureSialyltransferasesbeta-Galactoside alpha-2,3-SialyltransferaseLectinsSialyltransferasesST3GAL3 protein, humanT-Box Domain ProteinsTBR1 protein, human

Identifiers

PMID30089820
PMCPMC6244410
OpenAlexW2885545734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.