ArticleIndustrial health2019
Cardiac autonomic activity during simulated shift work.
Article in Industrial health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Cardiac autonomic activity during sleep deprivation with and without caffeine administration.Physiology & behavior · 2019Trial
- Sleep disruption from inhalation of biomass smoke: a basis for coincident hypertension?Particle and fibre toxicology · 2025Article
- Factors influencing heart rate variability in nurses following night shifts: a prospective observational clinical study.BMC nursing · 2025Article
- Association Between Depressive Symptoms and Altered Heart Rate Variability in Obstructive Sleep Apnea.Journal of clinical medicine · 2025Article
- The impact of working night shifts on cardiac autonomic nervous regulation during the six-minute walk test in nurses.BMC nursing · 2024Article
- Influence of sleep on physiological systems in atherosclerosis.Nature cardiovascular research · 2024Review
- Influence of night shift work on circadian heart-rate rhythm in nurses: using a Holter electrocardiogram that can be continuously measured for two weeks.Industrial health · 2024Article
- Influence of Night Shift Work on Heart Rate Variability in an Age- and Gender-Matched Study Group.Journal of cardiovascular development and disease · 2024Article
- A Narrative Review of Commercial Platforms Offering Tracking of Heart Rate Variability in Corporate Employees to Detect and Manage Stress.Journal of cardiovascular development and disease · 2023Article
- Mood Disorders are Correlated with Autonomic Nervous Function in Chronic Insomnia Patients with OSA.Nature and science of sleep · 2023Article
- Endogenous Diurnal Patterns of Adrenal and Gonadal Hormones During a 24-Hour Constant Routine After Simulated Shift Work.Journal of the Endocrine Society · 2022Article
- Working around the Clock: Is a Person's Endogenous Circadian Timing for Optimal Neurobehavioral Functioning Inherently Task-Dependent?Clocks & sleep · 2022Article
- Night shift schedule alters endogenous regulation of circulating cytokines.Neurobiology of sleep and circadian rhythms · 2021Article
- Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia.Nature communications · 2021Article
- Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans.Journal of pineal research · 2021Article
- Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues.International journal of molecular sciences · 2020Article
- Insomnia and circadian misalignment: an underexplored interaction towards cardiometabolic risk.Sleep science (Sao Paulo, Brazil)Review
- Circadian effects on UV-induced damage and mutations.Mutation research. Reviews in mutation researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Shift work leads to adverse health outcomes including increased risk of cardiovascular disease. Heart rate (HR) and heart rate variability (HRV) are measures of cardiac autonomic activity and markers of cardiovascular disease and mortality. To investigate the effects of shift work on cardiac autonomic activity, we assessed the influence of simulated night work on HR and HRV, and dissociated the direct effects of circadian misalignment from those of sleep displacement and altered physical activity patterns. A total of 29 subjects each participated in one of two in-laboratory, simulated shift work studies. In both studies, EKG was continuously monitored via Holter monitors to measure HR and the high frequency (HF) component of HRV (HF-HRV). We found endogenous circadian rhythmicity in HR and HF-HRV. Sleep and waking physical activity, both displaced during simulated night work, had more substantial, and opposite, effects on HR and HF-HRV. Our findings show systematic but complex, interacting effects of time of day, sleep/wake state, and physical activity on cardiac autonomic activity. These effects need to be taken into account when evaluating HR and HRV in shift work settings and when interpreting these measures of cardiac autonomic activity as markers of cardiovascular disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.