Evidence map›Paper›PMID 30089756›Full record

ArticleJournal of atherosclerosis and thrombosis2018

Relationship between Cardiorespiratory Fitness and Non-High-Density Lipoprotein Cholesterol: A Cohort Study.

Natsumi Watanabe, Susumu S Sawada, Kazunori Shimada, I-Min Lee, Yuko Gando, Haruki Momma, Ryoko Kawakami, Motohiko Miyachi, Yumiko Hagi, Chihiro Kinugawa and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Myocardial Performance in Elite Athletes: The Role of Homocysteine, Iron, and Lipids.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Natsumi WatanabeGraduate School of Health and Sports Science, Juntendo University.
Susumu S SawadaFaculty of Sport Sciences, Waseda University.
Kazunori ShimadaGraduate School of Health and Sports Science, Juntendo University.
I-Min LeeDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School.
Yuko GandoDepartment of Physical Activity Research, National Institutes of Biomedical Innovation, Health and Nutrition.
Haruki MommaDivision of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering.
Ryoko KawakamiFaculty of Sport Sciences, Waseda University.
Motohiko MiyachiDepartment of Physical Activity Research, National Institutes of Biomedical Innovation, Health and Nutrition.
Yumiko HagiDepartment of Sports & Leisure Management, Tokai University.
Chihiro KinugawaTokyo Gas Co., Ltd.
Takashi OkamotoTokyo Gas Co., Ltd.
Koji TsukamotoTokyo Gas Co., Ltd.
Steven N BlairArnold School of Public Health, University of South Carolina.
Tokyo Gas (Japan) · JPJuntendo University · JPNational Institute of Biomedical Innovation, Health and Nutrition · JPWaseda University · JPHarvard University · USTohoku University · JPTokai University · JPUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimRecent studies have suggested that non-high-density lipoprotein cholesterol (non-HDL-C) may be a good marker of coronary heart disease and cardiovascular disease risk. Therefore, we investigated the relationship between cardiorespiratory fitness (CRF) and non-HDL-C.

methodsWe evaluated CRF and the incidence of high level of non-HDL-C in 4,067 Japanese men without dyslipidemia. The participants were given a submaximal exercise test, a medical examination, and questionnaires on their health habits in 1986. A cycle ergometer was used to measure the CRF and maximal oxygen uptake was estimated. The incidence of a high level of non-HDL -C (≥170 mg/dL) from 1986 to 2006 was ascertained based on the fasting blood levels. A high level of non-HDL-C was found in 1,482 participants during the follow-up. Cox proportional hazard models were used to obtain the hazard ratios (HRs) and 95% confidence intervals (CIs) for the incidence of a high level of non-HDL-C.

resultsFollowing age adjustment, and using the lowest CRF group (quartile Ⅰ) as reference, the HRs and 95% CIs for quartiles II through IV were: 1.00 (95% CI: 0.87-1.15), 0.87 (95% CI: 0.76-1.00), and 0.70 (95% CI: 0.60-0.81), respectively (P for trend ＜0.001). After additional adjustment for body mass index, systolic blood pressure, smoking, alcohol intake, and family history of dyslipidemia, the HRs and 95% CIs were: 1.05 (95% CI: 0.92-1.21), 0.94 (95% CI: 0.81-1.08), and 0.79 (95% CI: 0.67-0.92), respectively (P for trend=0.001).

conclusionsThese results suggest that there is an inverse relationship between CRF levels and the incidence of a high level of non-HDL-C in Japanese men.

Indexed as

AdultBiomarkersCardiorespiratory FitnessCholesterolFollow-Up StudiesHumansLipoproteinsMalePrognosisProspective StudiesBiomarkersCholesterollipoprotein cholesterolLipoproteinsCholesterolCohort studyEpidemiologyExercise testNon-high-density lipoprotein cholesterol

Identifiers

PMID30089756
PMCPMC6249362
OpenAlexW2886788448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.