Evidence map›Paper›PMID 30089523›Full record

ArticleBMC health services research2018

Studying the impact of a medication use evaluation for polymedicated older patients by the community pharmacist (SIMENON): study protocol.

J Wuyts, J Maesschalck, I De Wulf, K Foubert, K Boussery, J De Lepeleire, V Foulon

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC health services research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03179722 (Studying the Impact of a Medication Use Evaluation by the Community Pharmacist), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03179722 nacompletednot on this map

Studying the Impact of a Medication Use Evaluation by the Community Pharmacist

TypeinterventionalSponsorJoke WuytsRan2016 to 2018Enrolled453ConditionsAgingArmsMedication review, Additional data collection: questionnaires
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. e-Interconsultations between a hospital pharmacy service and primary care pharmacy units in Spain.European journal of hospital pharmacy : science and practice · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J WuytsDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49 O&N2, Box 521, 3000, Leuven, Belgium. Joke.wuyts@kuleuven.be.ORCID 0000-0001-8831-6592
J MaesschalckAssociation of Belgian Pharmacies (APB), Archimedesstraat 11, 1000, Brussels, Belgium.
I De WulfAssociation of Belgian Pharmacies (APB), Archimedesstraat 11, 1000, Brussels, Belgium.
K FoubertPharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
K BousseryPharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
J De LepeleireDepartment Public Health and Primary Care, ACHG, KU Leuven, Leuven, Belgium.
V FoulonDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49 O&N2, Box 521, 3000, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAged polymedicated patients are particularly vulnerable for drug-related problems. A medication review aims to optimize the medication use of patients and improve health outcomes. In this study, the effect of a pharmacist-led medication use review is investigated for polymedicated ambulatory older patients with the aim of implementing this pharmaceutical care intervention across Belgium.

methodsThis article describes the study protocol of the SIMENON study and reports the results of the feasibility study, which aimed to test and optimize this study protocol. In the SIMENON intervention study, 75 Belgian community pharmacies each recruit 12 patients for a medication use review. For each patient, the identified drug-related problems and subsequent interventions are registered using the PharmDISC classification. In a subset of Dutch speaking patients, a pretest-posttest single group design is used to measure the impact of this review on patient related outcomes using questionnaires. The main outcome of the study is the type and number of drug-related problems and related interventions. A second outcome is the impact of the medication use review on adherence, objectively measured with dispensing data. Evolution in medication related quality of life is another outcome, measured with the Living with Medicines Questionnaire version 3. Other patient reported outcomes include adherence, self-management, patient satisfaction, fall incidents and use of emergency healthcare services. DISCUSSION: The findings of this study can provide data on the effectiveness of a medication use review in the Belgian primary care setting. Furthermore, it will provide insights in which patients benefit most of this intervention and therefore facilitate the implementation of medication review in Belgium.

trial registrationClinicalTrials.gov NCT03179722 . Retrospectively registered 7 June 2017.

Indexed as

PolypharmacyAgedBelgiumCommunity Pharmacy ServicesDrug MonitoringDrug UtilizationFeasibility StudiesHumansMulticenter Studies as TopicPatient SatisfactionPatient SelectionPharmaciesPharmacistsQuality of LifeRetrospective StudiesSurveys and QuestionnairesAgedCommunity pharmacistDrug-related problemsMedication reviewMedication use

Identifiers

PMID30089523
PMCPMC6083518

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.