Evidence map›Paper›PMID 30088934›Full record

ArticleOrganic letters2018

Eucalyptusdimers A-C, Dimeric Phloroglucinol-Phellandrene Meroterpenoids from Eucalyptus robusta.

Xu-Jie Qin, Mi-Yan Feng, Hui Liu, Wei Ni, Tyler Rauwolf, John A Porco, Huan Yan, Li He, Hai-Yang Liu

Abstract read
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  3. HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential ofAntibiotics (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Xu-Jie QinState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany , Chinese Academy of Sciences and Yunnan Key Laboratory of Natural Medicinal Chemistry , Kunming 650201 , People's Republic of China.
Mi-Yan FengState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany , Chinese Academy of Sciences and Yunnan Key Laboratory of Natural Medicinal Chemistry , Kunming 650201 , People's Republic of China.
Hui LiuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany , Chinese Academy of Sciences and Yunnan Key Laboratory of Natural Medicinal Chemistry , Kunming 650201 , People's Republic of China.
Wei NiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany , Chinese Academy of Sciences and Yunnan Key Laboratory of Natural Medicinal Chemistry , Kunming 650201 , People's Republic of China.
Tyler RauwolfDepartment of Chemistry, Center for Molecular Discovery (BU-CMD) , Boston University , 590 Commonwealth Avenue , Boston , Massachusetts 02215 , United States.
John A PorcoDepartment of Chemistry, Center for Molecular Discovery (BU-CMD) , Boston University , 590 Commonwealth Avenue , Boston , Massachusetts 02215 , United States.ORCID 0000-0002-2991-5680
Huan YanState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany , Chinese Academy of Sciences and Yunnan Key Laboratory of Natural Medicinal Chemistry , Kunming 650201 , People's Republic of China.
Li HeDepartment of Dermatology , The First Affiliated Hospital of Kunming Medical University , Kunming 650032 , People's Republic of China.
Hai-Yang LiuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany , Chinese Academy of Sciences and Yunnan Key Laboratory of Natural Medicinal Chemistry , Kunming 650201 , People's Republic of China.ORCID 0000-0002-1050-6254
Kunming Institute of Botany · CNBoston University · US

Funding

Chemical Synthesis of Complex Natural Products for Translational ScienceR35GM118173 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI JOHN A. PORCO · 2016 to 2026
$8.2M
NIGMS NIH HHS R35 GM118173
6 · The paper itself

Abstract

Eucalyptusdimers A-C, three dimeric phellandrene-derived meroterpenoids featuring an unprecedented, fused skeleton between two phellandrene and two acylphloroglucinol subunits, along with one biogenetically related intermediate, (±)-eucalyprobusone A, were isolated from the fruits of Eucalyptus robusta. Their structures and absolute configurations were elucidated using spectroscopic data, X-ray crystallography, and electronic circular dichroism analysis. The isolated meroterpenoids were evaluated for their anti-inflammatory, acetylcholinesterase inhibitory, and protein tyrosine phosphatase 1B inhibitory effects.

Identifiers

PMID30088934
PMCPMC6132224
OpenAlexW2885407430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.