Evidence map›Paper›PMID 30088680›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018

Molecular Encapsulation Inside Microtubules Based on Tau-Derived Peptides.

Hiroshi Inaba, Takahisa Yamamoto, Arif Md Rashedul Kabir, Akira Kakugo, Kazuki Sada, Kazunori Matsuura

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Lumenal components of cytoplasmic microtubules.Biochemical Society transactions · 2022
    Review
  8. Article
  9. Molecular swarm robots: recent progress and future challenges.Science and technology of advanced materials · 2020
    Review
  10. Article
  11. Review
  12. Molecular Encapsulation Inside Microtubules Based on Tau-Derived Peptides.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hiroshi InabaDepartment of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Koyama-Minami 4-101, Tottori, 680-8552, Japan.ORCID http://orcid.org/0000-0002-7658-7827
Takahisa YamamotoDepartment of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Koyama-Minami 4-101, Tottori, 680-8552, Japan.
Arif Md Rashedul KabirFaculty of Science, Hokkaido University, Kita 10 Nishi 8, Kita-ku, Sapporo, Hokkaido, 060-0810, Japan.ORCID http://orcid.org/0000-0001-6367-7690
Akira KakugoFaculty of Science, Hokkaido University, Kita 10 Nishi 8, Kita-ku, Sapporo, Hokkaido, 060-0810, Japan.ORCID http://orcid.org/0000-0002-1591-867X
Kazuki SadaFaculty of Science, Hokkaido University, Kita 10 Nishi 8, Kita-ku, Sapporo, Hokkaido, 060-0810, Japan.
Kazunori MatsuuraDepartment of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Koyama-Minami 4-101, Tottori, 680-8552, Japan.ORCID http://orcid.org/0000-0001-5472-7860
Tottori University · JPHokkaido University of Science · JPHokkaido University · JP

Funding

Japan Society for the Promotion of Science 17K14517
6 · The paper itself

Abstract

Microtubules are cytoskeletal filaments that serve as attractive scaffolds for developing nanomaterials and nanodevices because of their unique structural properties. The functionalization of the outer surface of microtubules has been established for this purpose. However, no attempts have been made to encapsulate molecules inside microtubules with 15 nm inner diameter. The encapsulation of various molecular cargos inside microtubules constitutes a new concept for nanodevice and nanocarrier applications of microtubules. Here, we developed peptide motifs for binding to the inner surface of microtubules, based on a repeat domain of the microtubule-associated protein Tau. One of the four Tau-derived peptides, 2

Indexed as

Amino Acid SequenceAnimalsDrug CarriersGoldMetal NanoparticlesMicrotubulesModels, MolecularNanostructuresNanotechnologyPeptidesSwinetau ProteinsTubulinDrug CarriersGoldPeptidestau ProteinsTubulingold nanoparticlemicrotubulesnanotechnologypeptideTau

Identifiers

PMID30088680
PMCPMC6220817
OpenAlexW2886354345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.