Evidence map›Paper›PMID 30088546›Full record

ArticleEinstein (Sao Paulo, Brazil)2018

Oral colonization by Candida species in HIV-positive patients: association and antifungal susceptibility study.

Letícia Silveira Goulart, Werika Weryanne Rosa de Souza, Camila Aoyama Vieira, Janaina Sousa de Lima, Ricardo Alves de Olinda, Claudinéia de Araújo

Abstract read
In one paragraph

Article in Einstein (Sao Paulo, Brazil), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Distribution ofHealthcare (Basel, Switzerland) · 2026
    Review
  3. International journal of molecular sciences · 2025
    Article
  4. Evaluation of Antifungal Activity AgainstHIV/AIDS (Auckland, N.Z.) · 2025
    Article
  5. Article
  6. Antifungal Susceptibility andBiomedicines · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. In Silico and In Vitro Analysis of Sulforaphane Anti-Antibiotics (Basel, Switzerland) · 2022
    Article
  13. Article
  14. Article
  15. Antifungal Resistance in Clinical Isolates ofJournal of fungi (Basel, Switzerland) · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Biofilm-ProducingHIV/AIDS (Auckland, N.Z.) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Letícia Silveira GoulartUniversidade Federal de Mato Grosso, Rondonópolis, MT, Brazil.ORCID http://orcid.org/0000-0003-1452-4908
Werika Weryanne Rosa de SouzaUniversidade Federal de Mato Grosso, Rondonópolis, MT, Brazil.ORCID http://orcid.org/0000-0001-6778-3837
Camila Aoyama VieiraUniversidade Federal de Mato Grosso, Rondonópolis, MT, Brazil.ORCID http://orcid.org/0000-0002-9333-7619
Janaina Sousa de LimaUniversidade Federal de Mato Grosso, Rondonópolis, MT, Brazil.ORCID http://orcid.org/0000-0003-3942-4583
Ricardo Alves de OlindaUniversidade Estadual da Paraíba, Campina Grande, PB, Brazil.ORCID http://orcid.org/0000-0002-0509-8428
Claudinéia de AraújoUniversidade Federal de Mato Grosso, Rondonópolis, MT, Brazil.ORCID http://orcid.org/0000-0002-3043-2731

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate antifungal susceptibility and factors associated with oral colonization by Candida species in HIV-positive patients.

methodsA prospective study based on convenience sampling of subjects recruited from a pool of confirmed HIV-positive individuals seen at a specialty outpatient service in Rondonópolis, Mato Grosso, Brazil). Oral swabs were collected from 197 patients. Candida species were identified by standard microbiological techniques (phenotypic and molecular methods). Antifungal susceptibility was investigated using the broth microdilution method.

resultsA total of 101 (51.3%) patients were Candida spp carriers. Candida albicans was the most prevalent species (80%). Patients aged 45 to 59 years (Prevalence ratios: 1.90; 95%CI: 1.57-6.31) and 60 years or older (Prevalence ratios: 4.43; 95%CI: 1.57-34.18) were at higher risk of oral colonization by Candida species. Resistance to fluconazole and ketoconazole, or to itraconazole, corresponded to 1% and 4%, respectively.

conclusionAge (45 years or older) was the only factor associated with oral colonization by Candida . Low rates of antifungal resistance to azoles were detected in yeast isolates obtained from HIV-positive patients. Findings of this study may contribute to proper therapeutic selection for oral candidiasis in HIV-positive patients.

Indexed as

Drug Resistance, FungalAdultAntifungal AgentsBrazilCandidaCandidiasis, OralFemaleFluconazoleHIV InfectionsHumansItraconazoleMaleMicrobial Sensitivity TestsMiddle AgedPrevalenceProspective StudiesAntifungal AgentsFluconazoleItraconazole

Identifiers

PMID30088546
PMCPMC6080703

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.