Evidence map›Paper›PMID 30088358›Full record

ArticleKorean circulation journal2018

Medical Resource Consumption and Quality of Life in Peripheral Arterial Disease in Korea: PAD Outcomes (PADO) Research.

Seung Woon Rha, Seung Hyuk Choi, Doo Il Kim, Dong Woon Jeon, Jae Hwan Lee, Kyung Soon Hong, Tae Joon Cha, Jang Hyun Cho, Sang Kon Lee, Yong Hwan Park and 6 more

Abstract read
In one paragraph

Article in Korean circulation journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Seung Woon RhaDivision of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
Seung Hyuk ChoiDivision of Cardiology, Department of Internal Medicine, Samsung Medical Center, Seoul, Korea.
Doo Il KimDivision of Cardiology, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea.
Dong Woon JeonDivision of Cardiology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Jae Hwan LeeDivision of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.
Kyung Soon HongDivision of Cardiology, Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea.
Tae Joon ChaDivision of Cardiology, Department of Internal Medicine, Kosin University, Gospel Hospital, Busan, Korea.
Jang Hyun ChoDivision of Cardiology, Department of Internal Medicine, St. Carollo Hospital, Suncheon, Korea.
Sang Kon LeeDivision of Cardiology, Department of Internal Medicine, Ulsan University Hospital, Ulsan, Korea.
Yong Hwan ParkDivision of Cardiology, Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
Woo Jung ParkDivision of Cardiology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.
Hyun Joo KimOutcomes Research and Real World Data, Pfizer Pharmaceuticals Korea Ltd., Seoul, Korea.
Young Joo KimOutcomes Research and Real World Data, Pfizer Pharmaceuticals Korea Ltd., Seoul, Korea.
Juneyoung LeeDepartment of Biostatistics, Korea University College of Medicine, Seoul, Korea.
Donghoon ChoiDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Korea. CDHLYJ@yuhs.ac.ORCID https://orcid.org/0000-0002-2009-9760
PADO research investigators

Funding

Pfizer Pharmaceuticals Korea LtdPfizer Pharmaceuticals Korea Ltd.
6 · The paper itself

Abstract

BACKGROUND AND

objectivesWe aimed to investigate the history of medical resource consumption and quality of life (QoL) in peripheral arterial disease (PAD) patients in Korea.

methodsThis was a prospective, multi-center (23 tertiary-hospitals, division of cardiology), non-interventional study. Adult patients (age ≥20 years) suffering from PAD for the last 12-month were enrolled in the study if they met with any of following; 1) ankle-brachial index (ABI) ≤0.9, 2) lower-extremity artery stenosis on computed tomography angiography ≥50%, or 3) peak-systolic-velocity-ratio (PSVR) on ultrasound ≥2.0. Medical chart review was used to assess patient characteristics/treatment patterns while the history of medical resource consumption and QoL data were collected using a patient survey. QoL was measured using EuroQoL-5-dimensions-3-level (EQ-5D-3L) score system, and the factors associated with QoL were analyzed using multiple linear regression analysis.

resultsThis study included 1,260 patients (age: 69.8 years, male: 77.0%). The most prevalent comorbidities were hypertension (74.8%), hyperlipidemia (51.0%) and diabetes-mellitus (50.2%). The 94.1% of the patients took pharmacotherapy including aspirin (76.2%), clopidogrel (53.3%), and cilostazol (33.6%). The 12.6% of the patients were receiving smoking cessation education/pharmacotherapy. A considerable number of patients (500 patients, 40.0%) had visit history to another hospital before diagnosis/treatment at the current hospital, with visits to orthopedic units (50.4%) being the most common. At the time, 29% (or higher) of the patients were already experiencing symptoms of critical limb ischemia. Baseline EQ-5D index and EQ VAS were 0.64±0.24 and 67.49±18.29. Factors significantly associated with QoL were pharmacotherapy (B=0.05053; p=0.044) compared to no pharmacotherapy, and Fontaine stage improvement/maintain stage I (B=0.04448; p<0.001) compared to deterioration/maintain stage II-IV.

conclusionsIncrease in disease awareness for earlier diagnosis and provision of adequate pharmacotherapy is essential to reduce disease burden and improve QoL of Korean PAD patients.

Indexed as

Disease burdenPeripheral arterial diseaseQuality of life

Identifiers

PMID30088358
PMCPMC6110706

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.