Evidence map›Paper›PMID 30088169›Full record

ArticleInflammation2018

Systemic Transplantation of Mesenchymal Stem Cells Modulates Endothelial Cell Adhesion Molecules Induced by Ovalbumin in Rat Model of Asthma.

Rana Keyhanmanesh, Reza Rahbarghazi, Mahdi Ahmadi

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rana KeyhanmaneshDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza RahbarghaziStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahdi AhmadiTuberculosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. mahdi59866@gmail.com.ORCID http://orcid.org/0000-0002-0774-9378
Tabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achieving the optimal clinical outcome of mesenchymal stem cells (MSCs) is particularly dependent on fundamental understanding of therapeutic mechanisms. The current study was focused on the possible mechanisms by which rat bone marrow-derived mesenchymal stem cells (rBMMSCs) and/or conditioned media (CM) display broad immunomodulatory properties for ameliorating of asthma-related pathological changes. Male rats were divided equally into four experimental groups (n = 6): healthy rats received 50 μl PBS intravenously (group C), sensitized rats received 50 μl PBS intravenously (group OVA), sensitized rats received 50 μl CM intravenously (group OVA + CM), and sensitized rats received 50 μl PBS intravenously containing 2 × 10

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsAsthmaCell Adhesion MoleculesCulture Media, ConditionedEndothelial CellsIntercellular Adhesion Molecule-1Interferon-gammaInterleukin-12Interleukin-5LungMaleMesenchymal Stem CellsOvalbuminRatsVascular Cell Adhesion Molecule-1Cell Adhesion MoleculesCulture Media, ConditionedIntercellular Adhesion Molecule-1Interferon-gammaInterleukin-12Interleukin-5OvalbuminVascular Cell Adhesion Molecule-1asthmaICAM-1interleukinmesenchymal stem cellsVCAM-1

Identifiers

PMID30088169
OpenAlexW2886512262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.