ReviewFrontiers in immunology2018
DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.
Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Multi-omics analysis reveals COVID-19 vaccine induced attenuation of inflammatory responses during breakthrough disease.Nature communications · 2024Trial
- Neutrophil-modulated Dicer expression in macrophages influences inflammation resolution.Cellular and molecular life sciences : CMLS · 2025Article
- DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology.Biology · 2025Review
- Regulation of the innate immune response in rheumatoid arthritis.Frontiers in immunology · 2025Review
- Expression characteristics, molecular mechanisms, and clinical significance of DICER1 in breast cancer.Frontiers in genetics · 2025Article
- New insights into the role of cellular senescence and rheumatic diseases.Frontiers in immunology · 2025Review
- Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration.Disease models & mechanisms · 2024Article
- Effect of ACADL on the differentiation of goat subcutaneous adipocyte.Animal bioscience · 2023Article
- The relationship between defects in DNA repair genes and autoinflammatory diseases.Rheumatology international · 2022Review
- MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.Frontiers in immunology · 2021Article
- Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations.Cellular and molecular life sciences : CMLS · 2020Review
- Decreased expression of miR-29 family associated with autoimmune myasthenia gravis.Journal of neuroinflammation · 2020Article
- Atypical Membrane-Anchored Cytokine MIF in a Marine Dinoflagellate.Microorganisms · 2020Article
- Review
- Dental abnormalities in individuals with pathogenic germline variation in DICER1.American journal of medical genetics. Part A · 2019Article
- Epigenome-wide association study reveals methylation pathways associated with childhood allergic sensitization.Epigenetics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loss-of-function or knockout mouse models have established a fundamental role for the RNAse III enzyme DICER1 in development and tissue morphogenesis and/or homeostasis. These functions are currently assumed to result mainly from the DICER1-dependent biogenesis of microRNAs which exhibit important gene expression regulatory properties. However, non-canonical DICER1 functions have recently emerged. These include interaction with the DNA damage response (DDR) pathway and the processing of cytotoxic non-coding RNAs, suggesting that DICER1 might also participate in the regulation of major cellular processes through miRNA-independent mechanisms. Recent findings indicated that reduced
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.