Evidence map›Paper›PMID 30087665›Full record

ArticleFrontiers in microbiology2018

Boldine-Derived Alkaloids Inhibit the Activity of DNA Topoisomerase I and Growth of

María T García, David Carreño, José M Tirado-Vélez, María J Ferrándiz, Liliana Rodrigues, Begoña Gracia, Mónica Amblar, José A Ainsa, Adela G de la Campa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Small Molecule Inhibitors ofInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Journal of clinical tuberculosis and other mycobacterial diseases · 2022
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

María T GarcíaUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
David CarreñoUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
José M Tirado-VélezUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
María J FerrándizUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Liliana RodriguesCIBER de Enfermedades Respiratorias, Madrid, Spain.
Begoña GraciaCIBER de Enfermedades Respiratorias, Madrid, Spain.
Mónica AmblarUnidad de Patología Molecular de Neumococo, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
José A AinsaCIBER de Enfermedades Respiratorias, Madrid, Spain.
Adela G de la CampaUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Centro Nacional de Microbiologia · ESInstituto de Salud Carlos III · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spread of multidrug-resistant isolates of

Indexed as

antituberculosis activityDNA supercoilingDNA topoisomerase I inhibitordrug discoveryMycobacterium tuberculosisN-methyl-seconeolitsineseconeolitsine

Identifiers

PMID30087665
PMCPMC6066988
OpenAlexW2884646159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.