Evidence map›Paper›PMID 30087614›Full record

ArticleFrontiers in pharmacology2018

Polypharmacology of Berberine Based on Multi-Target Binding Motifs.

Ming Chu, Xi Chen, Jing Wang, Likai Guo, Qianqian Wang, Zirui Gao, Jiarui Kang, Mingbo Zhang, Jinqiu Feng, Qi Guo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Advance in identified targets of berberine.Frontiers in pharmacology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. (Molecules (Basel, Switzerland) · 2023
    Article
  13. A Review ofMolecules (Basel, Switzerland) · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Berberine Suppresses Lung Metastasis of CancerFrontiers in pharmacology · 2022
    Article
  19. Synthesis and investigation of quadruplex-DNA-binding, 9-Beilstein journal of organic chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Ming ChuDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Xi ChenDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Jing WangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Likai GuoDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Qianqian WangDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Zirui GaoDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Jiarui KangDepartment of Pathology, First Affiliated Hospital of Chinese PLA General Hospital, Beijing, China.
Mingbo ZhangPharmacy Departments, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Jinqiu FengDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Qi GuoDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Binghua LiDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Chengrui ZhangDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Xueyuan GuoDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Zhengyun ChuPharmacy Departments, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Yuedan WangDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Peking University · CNLiaoning University of Traditional Chinese Medicine · CNFirst Affiliated Hospital of Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseberberinedrug-target spacemulti-target binding motifspolypharmacology

Identifiers

PMID30087614
PMCPMC6066535
OpenAlexW2884105320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.